The dosimetric accuracy of a commercial model-based dose calculation algorithm in modeling a six-groove direction modulated brachytherapy tandem applicator.

Objective.With advancements in high-dose rate brachytherapy, the clinical translation of intensity modulated brachytherapy (IMBT) innovations necessitates utilization of model-based dose calculation algorithms (MBDCA) for accurate and rapid dose calculations. This study uniquely benchmarks a commercial MBDCA, BrachyVision ACUROS^TM(BVA), against Monte Carlo (MC) simulations, evaluating dose distributions for a novel IMBT applicator, termed as thesix-grooveDirection Modulated Brachytherapy (DMBT) tandem, expanding beyond previous focus on partially shielded vaginal cylinder applicators, through a novel methodology.Approach.The DMBT tandem applicator, made of a tungsten alloy with six evenly spaced grooves, was simulated using the GEANT4 MC code. Subsequently, two main scenarios were created using the BVA and reproduced by the MC simulations: 'Source at the Center of the Water Phantom (SACWP)' and 'Source at the Middle of the Applicator (SAMA)' for three cubical virtual water phantoms (20 cm)³, (30 cm)³, and (40 cm)³. A track length estimator was utilized for dose calculation and 2D/3D scoring were performed. The difference in isodose surfaces/lines (i.e. coverage) at each voxel,ΔD_{Isodose Levels/Lines}, was thus calculated for relevant normalization points (r_ref).Results.The coverage was comparable, based on 2D scoring, between the BVA and MC isodose surfaces/lines for the region of clinical relevance, (i.e. within 5 cm radius from the source) withΔD_{Isodose Lines}(r_ref: 1 cm from the source) falling within 2% for the two scenarios for all phantom sizes. For the phantom (20 cm)³,ΔD_{Isodose Levels}(3D scoring) recorded the range [-3.0% +6.5%] ([-7.4% +7.3%]) for 95% of the voxels of the same scoring volume for the SACWP (SAMA) scenario.Significance.The results indicated that the BVA could render comparable coverage as compared to the MC simulations in the region of clinical relevance for different phantom sizes.ΔD_{Isodose Lines}may offer an advantageous metric for evaluation of MBDCAs in clinical setting.