洛哌丁胺诱发儿科急性胰腺炎。

Q3 Medicine

Irish medical journal Pub Date : 2024-09-26

G Bruno, G Marinotti

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引用次数: 0

摘要

病例：一名 13 岁男孩因误服 12 毫克盐酸洛哌丁胺而入院。他的主诉是腹痛，尤其是右下腹和上腹部疼痛。诊断：他被诊断为因服用洛哌丁胺而继发急性胰腺炎。他的脂肪酶和淀粉酶确实升高，显示出急性和可逆的趋势。通过血液化验和腹部X光检查，排除了感染和胆石症的可能：讨论：讨论：洛哌丁胺是一种阿片受体激动剂，作用于μ-阿片受体。洛哌丁胺是一种阿片受体激动剂，作用于μ-阿片受体，导致奥奇氏括约肌痉挛和功能障碍，造成胰腺引流受阻，引发急性胰腺炎。本病例报告显示了首例洛哌丁胺诱发急性胰腺炎的儿科病例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Loperamide induced acute pancreatitis in pediatrics.

Presentation: A 13-year-old boy was admitted to the hospital following an accidental ingestion of 12 mg of loperamide hydrochloride. His main complaint was abdominal pain, especially in his right hypochondrium and epigastrium.

Diagnosis: He was diagnosed with acute pancreatitis secondary to the use of loperamide. His lipase and amylase were indeed raised showing an acute and reversible trend. Infections and cholelithiasis were ruled out by blood tests and US abdomen.

Treatment: The patient was treated with a single dose of activated charcoal and improved with no further treatment.

Discussion: Loperamide is an opioid-receptor agonist and acts on the μ-opioid receptor. This causes spasms and dysfunction of the sphincter of Oddi resulting in obstruction of the pancreatic drainage and leading to acute pancreatitis. This case report shows the first case of loperamide induced acute pancreatitis in pediatrics.

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来源期刊

Irish medical journal Medicine-Medicine (all)

CiteScore

1.00

自引率

0.00%

发文量

139

期刊介绍： Since its inception in 1867, the Journal of the Medical Association of Ireland and now in its present format, the Irish Medical Journal, has provided the medical community in Ireland with an invaluable service. As one of the leading biomedical publications in Ireland, it has sought to continue the education of medical students and postgraduates through scientific research, review articles and updates on contemporary clinical practices while providing an ongoing forum for medical debate. A measure of our stature is that we are listed in the Index Medicus and issued annually with a citation factor from the Institute for Scientific Information.