{"title":"在初级保健中实施粪便免疫化学检验。","authors":"N Abdullah, J Crowley, M Buckley","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>The incidence of colorectal cancer (CRC) has increased globally, in particular patients under the age of fifty. This is a pilot study of a faecal immunochemical testing(FIT) service in primary care. The aim was to trial a FIT service for asymptomatic patients.</p><p><strong>Methods: </strong>We offered FIT kits to asymptomatic patients, aged between 40-75 years old during routine consultations. The number of FITs performed and the outcomes were reviewed. A cut-off of >10μg Hb/g faeces was defined as a positive result.</p><p><strong>Results: </strong>Overall 180 FIT kits were distributed, 7 duplicate tests were given. Of the 173 patients recruited, 142 (82%) samples were analysed in the lab. A total of 126 ( 88.7%) samples had a normal result, 8(5%) were rejected, 31 (17.9%) did not send their sample for analysis. A positive result was found in 8(5%), of these 6 (75%) underwent colonoscopy. No cancer was identified, 4 (50%) had polyps removed and 2 patients require follow up colonoscopy.</p><p><strong>Discussion: </strong>This study represents the first successful implementation of a FIT service in primary care in Ireland. There is a significant unmet need in this setting and strong scientific rationale for the use of FIT testing in general practice.</p>","PeriodicalId":14713,"journal":{"name":"Irish medical journal","volume":"117 8","pages":"1013"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Implementing Faecal Immunochemical Testing in Primary Care.\",\"authors\":\"N Abdullah, J Crowley, M Buckley\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>The incidence of colorectal cancer (CRC) has increased globally, in particular patients under the age of fifty. This is a pilot study of a faecal immunochemical testing(FIT) service in primary care. The aim was to trial a FIT service for asymptomatic patients.</p><p><strong>Methods: </strong>We offered FIT kits to asymptomatic patients, aged between 40-75 years old during routine consultations. The number of FITs performed and the outcomes were reviewed. A cut-off of >10μg Hb/g faeces was defined as a positive result.</p><p><strong>Results: </strong>Overall 180 FIT kits were distributed, 7 duplicate tests were given. Of the 173 patients recruited, 142 (82%) samples were analysed in the lab. A total of 126 ( 88.7%) samples had a normal result, 8(5%) were rejected, 31 (17.9%) did not send their sample for analysis. A positive result was found in 8(5%), of these 6 (75%) underwent colonoscopy. No cancer was identified, 4 (50%) had polyps removed and 2 patients require follow up colonoscopy.</p><p><strong>Discussion: </strong>This study represents the first successful implementation of a FIT service in primary care in Ireland. There is a significant unmet need in this setting and strong scientific rationale for the use of FIT testing in general practice.</p>\",\"PeriodicalId\":14713,\"journal\":{\"name\":\"Irish medical journal\",\"volume\":\"117 8\",\"pages\":\"1013\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Irish medical journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Irish medical journal","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
目的：大肠癌（CRC）的发病率在全球范围内呈上升趋势，尤其是 50 岁以下的患者。这是一项在初级保健中开展粪便免疫化学检验（FIT）服务的试点研究。目的是为无症状患者试用粪便免疫化学检测服务：方法：我们在常规咨询中为年龄在 40-75 岁之间的无症状患者提供 FIT 套件。我们对进行 FIT 的人数和结果进行了审查。以粪便中 Hb 含量大于 10μg/g 为阳性结果：结果：共发放了 180 套 FIT 试剂盒，7 次重复检测。在招募的 173 名患者中，142 人（82%）的样本在实验室进行了分析。共有 126 份样本（88.7%）结果正常，8 份样本（5%）被拒收，31 份样本（17.9%）未送去分析。结果呈阳性的有 8 人（5%），其中 6 人（75%）接受了结肠镜检查。其中 6 人（75%）接受了结肠镜检查，没有发现癌症，4 人（50%）切除了息肉，2 人需要接受后续结肠镜检查：本研究是爱尔兰首次在基层医疗机构成功实施 FIT 服务。在这种情况下，有大量需求未得到满足，而且在全科医疗中使用 FIT 检测有很强的科学依据。
Implementing Faecal Immunochemical Testing in Primary Care.
Aim: The incidence of colorectal cancer (CRC) has increased globally, in particular patients under the age of fifty. This is a pilot study of a faecal immunochemical testing(FIT) service in primary care. The aim was to trial a FIT service for asymptomatic patients.
Methods: We offered FIT kits to asymptomatic patients, aged between 40-75 years old during routine consultations. The number of FITs performed and the outcomes were reviewed. A cut-off of >10μg Hb/g faeces was defined as a positive result.
Results: Overall 180 FIT kits were distributed, 7 duplicate tests were given. Of the 173 patients recruited, 142 (82%) samples were analysed in the lab. A total of 126 ( 88.7%) samples had a normal result, 8(5%) were rejected, 31 (17.9%) did not send their sample for analysis. A positive result was found in 8(5%), of these 6 (75%) underwent colonoscopy. No cancer was identified, 4 (50%) had polyps removed and 2 patients require follow up colonoscopy.
Discussion: This study represents the first successful implementation of a FIT service in primary care in Ireland. There is a significant unmet need in this setting and strong scientific rationale for the use of FIT testing in general practice.
期刊介绍：
Since its inception in 1867, the Journal of the Medical Association of Ireland and now in its present format, the Irish Medical Journal, has provided the medical community in Ireland with an invaluable service. As one of the leading biomedical publications in Ireland, it has sought to continue the education of medical students and postgraduates through scientific research, review articles and updates on contemporary clinical practices while providing an ongoing forum for medical debate. A measure of our stature is that we are listed in the Index Medicus and issued annually with a citation factor from the Institute for Scientific Information.
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