类固醇依赖性肾病综合征患儿左旋咪唑诱发粒细胞减少症：病例报告。

IF 0.5 4区医学 Q3 Medicine

Journal of Nepal Medical Association Pub Date : 2024-07-31 DOI:10.31729/jnma.8700

Mohammad Firoz Anjum, Gaurav Kumar Gupta, Jeetendra Bhandari

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引用次数: 0

摘要

摘要：左旋咪唑是一种有效的免疫调节剂。左旋咪唑具有免疫刺激、免疫调节和节省类固醇的作用，因此被用于治疗肾病综合征。左旋咪唑常见的不良反应是胃肠道症状（恶心、腹部绞痛）和发热。然而，粒细胞减少症或泛血细胞减少症也是左旋咪唑的罕见并发症，但会危及生命。本病例报告了一名患有类固醇依赖性肾病综合征的 5 岁女童，她开始根据体重服用左旋咪唑后，每次就诊时白细胞总数水平都在下降。因此，本病例报告强调了识别这种罕见副作用及其处理方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Levamisole Induced Agranulocytosis in a Child with Steroid Dependent Nephrotic Syndrome: A Case Report.

Abstract: Levamisole has been used as an effective immunomodulator. Levamisole has been used for nephrotic syndrome due to its immunostimulant, immunomodulating, and steroid-sparing effects. Common adverse effects of levamisole are gastrointestinal symptoms (nausea, abdominal cramps), and pyrexia. However, agranulocytosis or pancytopenia is also a rare but life-threatening complication of levamisole. This is a case report of a 5-year-old girl who had steroid-dependent nephrotic syndrome for which she was started on levamisole as per her weight, following which she had falling total leukocyte count levels on every visit. Thus, this case report emphasizes identifying this rare side effect and its management.

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来源期刊

Journal of Nepal Medical Association PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-MEDICINE, GENERAL & INTERNAL

CiteScore

1.00

自引率

0.00%

发文量

233

审稿时长

>12 weeks

期刊介绍： Journal of Nepal Medical Association is an internationally peer-reviewed, MedLine/PubMed indexed, a monthly general medical journal published by Nepal Medical Association. JNMA is the first and oldest medical journal from Nepal since 1963 AD.