微碎屑脂肪组织可为膝关节炎疼痛提供一种有效的注射治疗方式,并在一年内改善疼痛和功能。

IF 4.4 1区 医学 Q1 ORTHOPEDICS
Mark Girard Siegel
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引用次数: 0

摘要

膝关节炎疼痛的注射疗法在不断发展。考虑到骨关节炎是成年患者最常见的骨科病症,这一点意义重大。据美国疾病控制和预防中心报告,16.9% 的成年人都会受到骨关节炎的影响,到 65 岁时,几乎一半的人都会经历与软骨退化有关的疼痛。类固醇注射只能在短期内改善症状。使用透明质酸盐进行粘度补充和注射富血小板血浆都显示出不一致的长期效果。最近的研究表明,在诊室注射微碎屑脂肪组织可在 6 个月和 12 个月后改善退行性关节病引起的膝关节疼痛患者的症状。还需要更多的研究来证实这一发现的可重复性。最重要的是,膝关节炎注射研究必须包括安慰剂对照(生理盐水注射),才能真正证明疗效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Editorial Commentary: Microfragmented Adipose Tissue May Provide an Effective Injection Treatment Modality for Arthritic Knee Pain With 1-Year Improvement in Pain and Function.

Injectable treatments for arthritic knee pain continue to evolve. This is significant, considering that osteoarthritis is the most common orthopaedic pathology in adult patients. The Centers for Disease Control and Prevention report that 16.9% of all adults are affected, and by age 65 years, almost one-half of the population will experience pain related to cartilage degradation. Steroid injections show only short-term improvements. Both viscosupplementation using hyaluronates and platelet-rich plasma injection show inconsistent long-term results. Recently microfragmented adipose tissue injections in the office setting have been shown to provide symptomatic improvement at 6 and 12 months in patients with knee pain from degenerative joint disease. Additional studies are needed to confirm the reproducibility of this finding. Most of all, study of injections for knee arthritis must include a placebo control (saline injection) to truly demonstrate efficacy.

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来源期刊
CiteScore
9.30
自引率
17.00%
发文量
555
审稿时长
58 days
期刊介绍: Nowhere is minimally invasive surgery explained better than in Arthroscopy, the leading peer-reviewed journal in the field. Every issue enables you to put into perspective the usefulness of the various emerging arthroscopic techniques. The advantages and disadvantages of these methods -- along with their applications in various situations -- are discussed in relation to their efficiency, efficacy and cost benefit. As a special incentive, paid subscribers also receive access to the journal expanded website.
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