压力性尿失禁手术治疗的最新进展。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
ACS Applied Bio Materials Pub Date : 2024-12-01 Epub Date: 2024-09-07 DOI:10.1097/GCO.0000000000000989
Kelsey Gallo, Hillary Weiner, Kavita Mishra
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引用次数: 0

摘要

审查目的:压力性尿失禁(SUI)是一种常见疾病,女性通常会选择手术治疗。几十年来,合成尿道中段吊带(MUS)一直是主要的治疗方法。单切口吊带(SIS)的出现降低了在放置尿道中段吊带时与套管通过相关的发病率。尿道膨出术由于治愈率较低而较少使用。最近出现了支持单切口吊带(SIS)和使用 Bulkamid 聚丙烯酰胺水凝胶(PAHG)进行尿道膨出的新数据:一些随访时间≥10 年的研究表明,随着时间的推移,耻骨后(RMUS)和经尿道(TMUS)尿道中段吊带的疗效和并发症发生率趋于稳定。SIS 产品在长达 3 年的随访中显示出与传统 TMUS 和 RMUS 相当的疗效,并且可以在局部麻醉下放置。与吊带相比,使用 PAHG 进行尿道膨出的治愈率较低,但满意率很高,随访 7 年后,有反应者的情况会得到持续改善。摘要:TMUS、RMUS 和 SIS 这三种可用的吊带目前都被认为是治疗 SUI 的合适手术选择。虽然由于缺乏比较数据,不能正式推荐使用哪种注射剂,但使用 PAHG 进行尿道膨出具有良好的长期效果和出色的安全性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An update on surgical management for stress urinary incontinence.

Purpose of review: Stress urinary incontinence (SUI) is a common condition for which women often opt for surgical management. Synthetic midurethral slings (MUS) have been the dominant treatment for decades. Single-incision slings (SIS) have been introduced to lower the morbidity associated with trocar passage during MUS placement. Urethral bulking has been used less frequently owing to its lower cure rates. New data have recently emerged in support of single-incision slings (SIS) and urethral bulking with Bulkamid polyacrylamide hydrogel (PAHG).

Recent findings: Several studies with a follow-up ≥10 years have shown stable efficacy and complication rates of retropubic (RMUS) and transobturator (TMUS) midurethral slings over time. SIS products show equivalent efficacy to traditional TMUS and RMUS at up to 3 years of follow-up and can be placed under local anesthesia. While urethral bulking with PAHG results in lower cure rates compared to slings, satisfaction rates are high and responders have sustained improvement at 7 years follow-up.

Summary: All three types of available slings, TMUS, RMUS, and SIS, are now considered appropriate surgical options for the treatment of SUI. Although the absence of comparative data precludes a formal recommendation for one injectable over another, urethral bulking with PAHG has favorable long-term results and an excellent safety profile.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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