{"title":"慢性伤口和疤痕管理的当前趋势回顾。","authors":"Chantalle Crous, Judey Pretorius, Anél Petzer","doi":"10.25270/wmp.24010","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Aberrant tissue repair can result in the formation of chronic wounds and pathological scarring, which can severely impact a patient's quality of life. Due to their complexity, treatment of these conditions remains challenging.</p><p><strong>Purpose: </strong>This review article provides a brief overview of the various treatments with regards to application, possible mechanism(s) of action, new developments, and areas requiring further research.</p><p><strong>Methods: </strong>A literature review on the different therapies/products currently used for chronic wounds and pathological scars was conducted. Several databases-including PubMed, ScienceDirect, Web of Science, and Google Scholar-were searched to find relevant articles on this topic.</p><p><strong>Results: </strong>Numerous products and treatment options, including several promising new technologies, are currently available. These therapies/products aim to accelerate wound healing, reduce scarring, and ultimately reach the goal of scarless tissue regeneration.</p><p><strong>Conclusion: </strong>Currently, no gold standard therapy exists for chronic wounds and pathological scars. Existing treatments demonstrate varying levels of efficacy, and further research is required regarding their safety and molecular mechanism(s) of action.</p>","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A review of the current trends in chronic wound and scar management.\",\"authors\":\"Chantalle Crous, Judey Pretorius, Anél Petzer\",\"doi\":\"10.25270/wmp.24010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Aberrant tissue repair can result in the formation of chronic wounds and pathological scarring, which can severely impact a patient's quality of life. Due to their complexity, treatment of these conditions remains challenging.</p><p><strong>Purpose: </strong>This review article provides a brief overview of the various treatments with regards to application, possible mechanism(s) of action, new developments, and areas requiring further research.</p><p><strong>Methods: </strong>A literature review on the different therapies/products currently used for chronic wounds and pathological scars was conducted. Several databases-including PubMed, ScienceDirect, Web of Science, and Google Scholar-were searched to find relevant articles on this topic.</p><p><strong>Results: </strong>Numerous products and treatment options, including several promising new technologies, are currently available. These therapies/products aim to accelerate wound healing, reduce scarring, and ultimately reach the goal of scarless tissue regeneration.</p><p><strong>Conclusion: </strong>Currently, no gold standard therapy exists for chronic wounds and pathological scars. Existing treatments demonstrate varying levels of efficacy, and further research is required regarding their safety and molecular mechanism(s) of action.</p>\",\"PeriodicalId\":23741,\"journal\":{\"name\":\"Wound management & prevention\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Wound management & prevention\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.25270/wmp.24010\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wound management & prevention","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.25270/wmp.24010","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
背景:组织修复失常可导致慢性伤口和病理性瘢痕的形成,严重影响患者的生活质量。目的:这篇综述文章简要概述了各种治疗方法的应用、可能的作用机制、新进展以及需要进一步研究的领域:方法:对目前用于慢性伤口和病理性疤痕的各种疗法/产品进行了文献综述。搜索了多个数据库,包括 PubMed、ScienceDirect、Web of Science 和 Google Scholar,以查找与该主题相关的文章:结果:目前有许多产品和治疗方案,包括几种前景看好的新技术。这些疗法/产品旨在加速伤口愈合、减少疤痕,并最终实现无疤痕组织再生的目标:目前,慢性伤口和病理性疤痕还没有金标准疗法。结论:目前,慢性伤口和病理性疤痕的治疗还没有金标准,现有的治疗方法显示出不同程度的疗效,其安全性和分子作用机制还需要进一步研究。
A review of the current trends in chronic wound and scar management.
Background: Aberrant tissue repair can result in the formation of chronic wounds and pathological scarring, which can severely impact a patient's quality of life. Due to their complexity, treatment of these conditions remains challenging.
Purpose: This review article provides a brief overview of the various treatments with regards to application, possible mechanism(s) of action, new developments, and areas requiring further research.
Methods: A literature review on the different therapies/products currently used for chronic wounds and pathological scars was conducted. Several databases-including PubMed, ScienceDirect, Web of Science, and Google Scholar-were searched to find relevant articles on this topic.
Results: Numerous products and treatment options, including several promising new technologies, are currently available. These therapies/products aim to accelerate wound healing, reduce scarring, and ultimately reach the goal of scarless tissue regeneration.
Conclusion: Currently, no gold standard therapy exists for chronic wounds and pathological scars. Existing treatments demonstrate varying levels of efficacy, and further research is required regarding their safety and molecular mechanism(s) of action.