基于可解释人工智能的优化 DeepLabV3+ 和解释网络信息融合的核磁共振成像扫描多模态脑肿瘤分割和分类。

IF 7 2区 医学 Q1 BIOLOGY
Computers in biology and medicine Pub Date : 2024-11-01 Epub Date: 2024-10-02 DOI:10.1016/j.compbiomed.2024.109183
Muhammad Sami Ullah, Muhammad Attique Khan, Hussain Mobarak Albarakati, Robertas Damaševičius, Shrooq Alsenan
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引用次数: 0

摘要

可解释人工智能(XAI)旨在提供机器学习(ML)方法,使人们能够理解、正确信任并创建更多可解释的模型。在医学影像领域,XAI 已被用于解释深度学习黑盒模型,以证明机器决策和预测的可信度。在这项工作中,我们提出了一个基于深度学习和可解释人工智能的框架,用于分割和分类脑肿瘤。该框架由两部分组成。第一部分是基于 DeepLabv3+ 架构的编码器-解码器,通过基于贝叶斯优化(BO)的超参数初始化来实现。通过 Atrous Spatial Pyramid Pooling(ASPP)技术提取不同尺度的特征。提取的特征被传递到输出层进行肿瘤分割。在拟议框架的第二部分,提出了两个定制模型,分别名为 "96 层倒置残余瓶颈(IRB-96)"和 "倒置残余瓶颈自注意(IRB-Self)"。这两个模型都是在选定的脑肿瘤数据集上进行训练,并从全局平均汇集层和自我注意层提取特征。使用串行方法融合特征并进行分类。对神经网络分类器进行了基于 BO 的超参数优化,并对分类结果进行了优化。此外,还采用了一种名为 LIME 的 XAI 方法来检查所提模型的可解释性。在 Figshare 数据集上对所提出的框架进行了实验,结果显示平均分割准确率为 92.68%,平均分类准确率为 95.42%。与最先进的技术相比,所提出的框架提高了准确率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multimodal brain tumor segmentation and classification from MRI scans based on optimized DeepLabV3+ and interpreted networks information fusion empowered with explainable AI.

Explainable artificial intelligence (XAI) aims to offer machine learning (ML) methods that enable people to comprehend, properly trust, and create more explainable models. In medical imaging, XAI has been adopted to interpret deep learning black box models to demonstrate the trustworthiness of machine decisions and predictions. In this work, we proposed a deep learning and explainable AI-based framework for segmenting and classifying brain tumors. The proposed framework consists of two parts. The first part, encoder-decoder-based DeepLabv3+ architecture, is implemented with Bayesian Optimization (BO) based hyperparameter initialization. The different scales are performed, and features are extracted through the Atrous Spatial Pyramid Pooling (ASPP) technique. The extracted features are passed to the output layer for tumor segmentation. In the second part of the proposed framework, two customized models have been proposed named Inverted Residual Bottleneck 96 layers (IRB-96) and Inverted Residual Bottleneck Self-Attention (IRB-Self). Both models are trained on the selected brain tumor datasets and extracted features from the global average pooling and self-attention layers. Features are fused using a serial approach, and classification is performed. The BO-based hyperparameters optimization of the neural network classifiers is performed and the classification results have been optimized. An XAI method named LIME is implemented to check the interpretability of the proposed models. The experimental process of the proposed framework was performed on the Figshare dataset, and an average segmentation accuracy of 92.68 % and classification accuracy of 95.42 % were obtained, respectively. Compared with state-of-the-art techniques, the proposed framework shows improved accuracy.

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来源期刊
Computers in biology and medicine
Computers in biology and medicine 工程技术-工程:生物医学
CiteScore
11.70
自引率
10.40%
发文量
1086
审稿时长
74 days
期刊介绍: Computers in Biology and Medicine is an international forum for sharing groundbreaking advancements in the use of computers in bioscience and medicine. This journal serves as a medium for communicating essential research, instruction, ideas, and information regarding the rapidly evolving field of computer applications in these domains. By encouraging the exchange of knowledge, we aim to facilitate progress and innovation in the utilization of computers in biology and medicine.
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