线粒体功能障碍对男性不育有多大影响？

IF 1.4 Q3 UROLOGY & NEPHROLOGY

Archivio Italiano di Urologia e Andrologia Pub Date : 2024-10-02 DOI:10.4081/aiua.2024.12837

Ernesto Di Mauro, Gainlugi Cacace, Vincenzo Morgera, Roberto La Rocca, Luigi Napolitano, Pietro Saldutto, Vincenzo Maria Altieri

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引用次数: 0

摘要

不孕症通常是指夫妻双方在无保护措施的情况下频繁性交 1 年后仍无法受孕。约 20% 的病例完全由男性造成。泌尿生殖系统异常、内分泌疾病、环境毒素、遗传疾病、免疫因素、泌尿生殖系统感染、性功能障碍等几种危险因素都被认为是导致男性不育的原因。目前，不同的研究报告称，睾丸冷冻功能障碍是导致男性不育和精液参数改变的原因。

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How much does mitochondrial dysfunction affect male infertility?

Infertility is usually defined as the inability of a couple to conceive even after 1 year of unprotected, frequent sexual intercourse. The male is solely responsible in about 20% of cases. Several risk factors as well as urogenital abnormalities,endocrinological disease,enviromental toxines,genetic disorders,immunological factors,urogenitaly infections,sexual dysfunction have been identified as causes of male infertility. Nowadays different studies reported mithocoldrial dysfunction as cause of male infertility and alteration of semen parameters.

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来源期刊

Archivio Italiano di Urologia e Andrologia UROLOGY & NEPHROLOGY-

CiteScore

2.10

自引率

35.70%

发文量

审稿时长

10 weeks