原发性醛固酮增多症肾上腺切除术后高血压缓解的预测:争议和悬而未决的问题叙述性综述。

IF 2.1 3区 医学 Q2 SURGERY
Luigi Marzano
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引用次数: 0

摘要

背景:原发性醛固酮增多症(PA)患者肾上腺切除术后的高血压缓解仍是一项严峻的临床挑战。术前确定哪些患者的血压会恢复正常既是当务之急,也是争议焦点。在这篇叙述性综述中,我们探讨了有关预测 PA 患者肾上腺切除术后高血压缓解的争议和未决问题:我们进行了全面的文献综述,重点关注 1954 年至 2024 年间发表的研究,评估了所有讨论 PA 患者肾上腺切除术后高血压缓解预测模型的研究。检索的数据库包括 MEDLINE®、Ovid Embase 和 Web of Science 数据库:结果:综述发现了几种高血压缓解的预测因素和预测模型,包括女性性别、高血压持续时间、抗高血压药物和体重指数。然而,研究设计和患者人群的不一致导致了不同的结论:结论:虽然 PA 患者肾上腺切除术后高血压缓解的某些预测因素和预测模型有证据支持,但仍存在重大争议和未解决的问题。虽然目前的预测模型提供了有价值的见解,但该领域显然需要进一步研究。未来的研究应侧重于验证和完善这些模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Predicting the resolution of hypertension following adrenalectomy in primary aldosteronism: Controversies and unresolved issues a narrative review.

Background: Hypertension resolution following adrenalectomy in patients with primary aldosteronism (PA) remains a critical clinical challenge. Identifying preoperatively which patients will become normotensive is both a priority and a point of contention. In this narrative review, we explore the controversies and unresolved issues surrounding the prediction of hypertension resolution after adrenalectomy in PA.

Methods: A comprehensive literature review was conducted, focusing on studies published between 1954 and 2024 that evaluated all studies that discussed predictive models for hypertension resolution post-adrenalectomy in PA patients. Databases searched included MEDLINE®, Ovid Embase, and Web of Science databases.

Results: The review identified several predictors and predictive models of hypertension resolution, including female sex, duration of hypertension, antihypertensive medication, and BMI. However, inconsistencies in study designs and patient populations led to varied conclusions.

Conclusions: Although certain predictors and predictive models of hypertension resolution post-adrenalectomy in PA patients are supported by evidence, significant controversies and unresolved issues remain. While the current predictive models provide valuable insights, there is a clear need for further research in this area. Future studies should focus on validating and refining these models.

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来源期刊
CiteScore
3.30
自引率
8.70%
发文量
342
审稿时长
4-8 weeks
期刊介绍: Langenbeck''s Archives of Surgery aims to publish the best results in the field of clinical surgery and basic surgical research. The main focus is on providing the highest level of clinical research and clinically relevant basic research. The journal, published exclusively in English, will provide an international discussion forum for the controlled results of clinical surgery. The majority of published contributions will be original articles reporting on clinical data from general and visceral surgery, while endocrine surgery will also be covered. Papers on basic surgical principles from the fields of traumatology, vascular and thoracic surgery are also welcome. Evidence-based medicine is an important criterion for the acceptance of papers.
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