对用于点扫描质子疗法日常质量保证的原型阵列进行评估。

IF 2 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Veronika Flatten, Henry-Aravinth Devendranath, Janik Kroh, Matthias Witt, Kilian-Simon Baumann, Kenneth Gall, Bill Simon, Jörg Wulff, Andreas A. Schoenfeld
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引用次数: 0

摘要

背景:日常质量保证(QA)是放射治疗的一项基本任务。目的:本研究旨在根据 AAPM TG 224 推荐的参数(即剂量输出恒定性、光斑位置和远端范围验证),鉴定和评估用于铅笔束扫描质子治疗(PBS)日常质量保证任务的原型。此外,还为原型建立了一种省时的校准方法,以实现快速可靠的日常质量保证程序:方法:首先,设计并评估了校准程序,该程序可确定阵列响应的特征,并可将测量信号转换为临床所需的质量保证参数。最后,开发并测试了一种省时、省资源的日常质量保证程序:结果:原型阵列能以亚毫米级的精度分辨光斑位置偏差,以及光斑大小在全宽域(FWHM)上的变化,灵敏度为 2 %($/%$)。还能以亚毫米级的精度评估不同深度的范围和能量。经过一些培训后,原型设备的安装大约需要两分钟,回旋加速器的总光束时间大约为一分钟,同步加速器的总光束时间大约为五分钟:对用于点扫描质子治疗的日常质量保证原型进行了评估,该原型的特点是安装快速简便,可以测量相关的束流参数,通常在不到一分钟的束流时间内即可完成。AAPM TG 224 报告推荐的所有质量保证参数都能得到足够准确的分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Evaluation of a prototype array for daily quality assurance in spot scanning proton therapy

Evaluation of a prototype array for daily quality assurance in spot scanning proton therapy

Background

Quality assurance (QA) on a daily basis is an essential task in radiotherapy. In pencil beam scanning proton therapy (PBS), there is a lack of available practical QA devices for routine daily QA in comparison to conventional radiotherapy.

Purpose

The aim was to characterize and evaluate a prototype for the task of daily QA routine for PBS with parameters recommended by the AAPM TG 224, that is, the dose output constancy, the spot position and the distal range verification. Furthermore, a time efficient calibration method for fast and reliable daily QA routine was established for the prototype.

Methods

First, a calibration routine was designed and evaluated, which characterizes the array response and allows for a conversion of the measured signal to clinically needed QA parameters. Finally, a time and resource efficient daily QA routine was developed and tested.

Results

The prototype array can distinguish spot position deviations with sub-millimeter accuracy, as well as changes in the spot size in terms of FWHM with a 2 % $\%$ sensitivity. The range and thus the energy can be evaluated at different depths also with sub-millimeter precision. After some training, the setup of the prototype device took roughly two minutes and the total beamtime was about one minute on cyclotron site and five minutes for synchrotrons.

Conclusions

A prototype for daily QA in spot scanning proton therapy was evaluated, which features a fast and easy setup and allows for measuring relevant beam parameters, typically within less than a minute of beam time. All QA parameters as recommended by the AAPM TG 224 report can be analyzed with sufficient accuracy.

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来源期刊
CiteScore
3.60
自引率
19.00%
发文量
331
审稿时长
3 months
期刊介绍: Journal of Applied Clinical Medical Physics is an international Open Access publication dedicated to clinical medical physics. JACMP welcomes original contributions dealing with all aspects of medical physics from scientists working in the clinical medical physics around the world. JACMP accepts only online submission. JACMP will publish: -Original Contributions: Peer-reviewed, investigations that represent new and significant contributions to the field. Recommended word count: up to 7500. -Review Articles: Reviews of major areas or sub-areas in the field of clinical medical physics. These articles may be of any length and are peer reviewed. -Technical Notes: These should be no longer than 3000 words, including key references. -Letters to the Editor: Comments on papers published in JACMP or on any other matters of interest to clinical medical physics. These should not be more than 1250 (including the literature) and their publication is only based on the decision of the editor, who occasionally asks experts on the merit of the contents. -Book Reviews: The editorial office solicits Book Reviews. -Announcements of Forthcoming Meetings: The Editor may provide notice of forthcoming meetings, course offerings, and other events relevant to clinical medical physics. -Parallel Opposed Editorial: We welcome topics relevant to clinical practice and medical physics profession. The contents can be controversial debate or opposed aspects of an issue. One author argues for the position and the other against. Each side of the debate contains an opening statement up to 800 words, followed by a rebuttal up to 500 words. Readers interested in participating in this series should contact the moderator with a proposed title and a short description of the topic
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