Luz Divina Juez, Ana Del Carmen Ortega, Pablo Priego, Juan Carlos García Pérez, José María Fernández-Cebrián, Jose I Botella-Carretero
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引用次数: 0
摘要
肌营养不良性肥胖（Sarcopenic obesity，SO）是一种新的疾病，其定义包括营养不良患者的超重诊断。本综述旨在评估食管胃肿瘤（EGT）患者的身体成分对围手术期和肿瘤治疗效果的影响。本系统性综述根据 PRISMA 指南进行。检索了MEDLINE（PubMed）、Embase、Web of Science和SCOPUS数据库，检索期至2024年1月。最终确定了 16 篇文章，对 5378 名患者进行了分析。SO的患病率为10%（95%CI：6-16；I2 = 94%）。术前诊断出 SO 与严重术后并发症风险增加两倍有关（OR 2.32 [95%CI 1.41-3.82] I2 = 70%）。总体生存结果的 Meta 分析表明，SO 与总体生存率降低有关（HR 2.30；95%CI 1.46-3.61）。
Impact of sarcopenic obesity on surgical complications and oncologic outcomes of upper gastrointestinal tumors: a systematic review and meta-analysis.
Sarcopenic obesity (SO) is a new entity whose definition encompasses the diagnosis of overweight in malnourished patients. The aim of the review was to assess the impact of body composition in patients with esophago-gastric tumors (EGT) on perioperative and oncological outcomes. This systematic review was conducted under the PRISMA guidelines. MEDLINE (PubMed), Embase, Web of Science and SCOPUS databases were searched until January 2024. Sixteen articles were identified for analysis analyzing 5,378 patients. The prevalence of SO was 10% (95%CI: 6-16; I2 = 94%). Preoperative diagnosis of SO was associated with a twofold increased risk of severe postoperative complications (OR 2.32 [95%CI 1.41-3.82] I2 = 70%). Meta-analysis of overall survival outcomes identified that SO was associated with worse overall survival (HR 2.30; 95%CI 1.46-3.61).
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