在山羊模型中,半月板后根与骨的术后愈合在24周时仍不完全。

IF 4.4 1区 医学 Q1 ORTHOPEDICS
Jessica R Stambaugh, Reinaldo Colon-Morillo, L Alejandro Culebras Almeida, Farah Selman, Nicholas P J Perry
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引用次数: 0

摘要

许多骨科手术的目标是在足够长的时间内以机械方式稳定组织,使其发生生物愈合。在机械装置(螺钉、缝合线、锚等)最终失效之前,愈合的组织应能承受负荷。最近的研究表明,在山羊模型中,半月板后根部与骨骼的修复在术后 24 周(缝线拆除后,接受生物力学和组织学测试)仍未完全愈合。此外,术后 24 个月的核磁共振成像显示半月板持续挤压,但仅限于机械负荷下。当然,在临床实践中,修复缝线并不会被拆除,而是继续提供机械稳定性,直到缝线失效、组织-缝线界面失效或半月板根部愈合到足以抵抗负荷为止。尽管如此,我们仍需注意人类患者的愈合、负重和恢复活动所需的时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Editorial Commentary: Meniscal Posterior Root to Bone Postoperative Healing Appears Incomplete at 24 Weeks in a Goat Model.

The goal of many orthopaedic surgeries is to mechanically stabilize the tissue long enough for biological healing to occur. The healed tissue should be able to bear the load before the mechanical device (screw, suture, anchor, etc.) eventually fails. Recent research shows that in a goat model, meniscus posterior root repair to bone is not fully healed at 24 weeks postoperatively (after the suture is removed and under biomechanical and histologic testing). In addition, magnetic resonance imaging at 24 months postoperatively showed persistent meniscal extrusion but only under mechanical loading. Of course, in clinical practice, repair sutures are not removed and continue to provide mechanical stability until they either fail, the tissue-suture interface fails, or the meniscus root is healed enough to resist the load. Nevertheless, we need to be mindful of time to healing, weightbearing, and return to activity in human patients.

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来源期刊
CiteScore
9.30
自引率
17.00%
发文量
555
审稿时长
58 days
期刊介绍: Nowhere is minimally invasive surgery explained better than in Arthroscopy, the leading peer-reviewed journal in the field. Every issue enables you to put into perspective the usefulness of the various emerging arthroscopic techniques. The advantages and disadvantages of these methods -- along with their applications in various situations -- are discussed in relation to their efficiency, efficacy and cost benefit. As a special incentive, paid subscribers also receive access to the journal expanded website.
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