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引用次数: 0
摘要
针对已知相关矩阵的多元正态均值与双侧替代值的同步检验,本文介绍了经证实可对误差发现率进行有限样本控制的新方法。这些方法是通过将每个 p 值向左移动,并根据这些移动的 p 值考虑 Benjamini-Hochberg 型线性阶跃过程而得到的。每个 p 值的移动量可根据相关矩阵适当确定,以实现所需的误发现率控制。模拟研究和实际数据应用表明,与相关竞争者相比,所提出的方法具有良好的性能。
Shifted BH methods for controlling false discovery rate in multiple testing of the means of correlated normals against two-sided alternatives
For simultaneous testing of multivariate normal means with known correlation matrix against two-sided alternatives, this paper introduces new methods with proven finite-sample control of false discovery rate. The methods are obtained by shifting each -value to the left and considering a Benjamini–Hochberg-type linear step-up procedure based on these shifted -values. The amount of shift for each -value is appropriately determined from the correlation matrix to achieve the desired false discovery rate control. Simulation studies and real-data application show favorable performances of the proposed methods when compared with relevant competitors.
期刊介绍:
The Journal of Statistical Planning and Inference offers itself as a multifaceted and all-inclusive bridge between classical aspects of statistics and probability, and the emerging interdisciplinary aspects that have a potential of revolutionizing the subject. While we maintain our traditional strength in statistical inference, design, classical probability, and large sample methods, we also have a far more inclusive and broadened scope to keep up with the new problems that confront us as statisticians, mathematicians, and scientists.
We publish high quality articles in all branches of statistics, probability, discrete mathematics, machine learning, and bioinformatics. We also especially welcome well written and up to date review articles on fundamental themes of statistics, probability, machine learning, and general biostatistics. Thoughtful letters to the editors, interesting problems in need of a solution, and short notes carrying an element of elegance or beauty are equally welcome.