{"title":"在对相关常模的均值进行双侧替代多重检验时控制误发现率的偏移 BH 方法","authors":"Sanat K. Sarkar, Shiyu Zhang","doi":"10.1016/j.jspi.2024.106238","DOIUrl":null,"url":null,"abstract":"<div><div>For simultaneous testing of multivariate normal means with known correlation matrix against two-sided alternatives, this paper introduces new methods with proven finite-sample control of false discovery rate. The methods are obtained by shifting each <span><math><mi>p</mi></math></span>-value to the left and considering a Benjamini–Hochberg-type linear step-up procedure based on these shifted <span><math><mi>p</mi></math></span>-values. The amount of shift for each <span><math><mi>p</mi></math></span>-value is appropriately determined from the correlation matrix to achieve the desired false discovery rate control. Simulation studies and real-data application show favorable performances of the proposed methods when compared with relevant competitors.</div></div>","PeriodicalId":0,"journal":{"name":"","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Shifted BH methods for controlling false discovery rate in multiple testing of the means of correlated normals against two-sided alternatives\",\"authors\":\"Sanat K. Sarkar, Shiyu Zhang\",\"doi\":\"10.1016/j.jspi.2024.106238\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>For simultaneous testing of multivariate normal means with known correlation matrix against two-sided alternatives, this paper introduces new methods with proven finite-sample control of false discovery rate. The methods are obtained by shifting each <span><math><mi>p</mi></math></span>-value to the left and considering a Benjamini–Hochberg-type linear step-up procedure based on these shifted <span><math><mi>p</mi></math></span>-values. The amount of shift for each <span><math><mi>p</mi></math></span>-value is appropriately determined from the correlation matrix to achieve the desired false discovery rate control. Simulation studies and real-data application show favorable performances of the proposed methods when compared with relevant competitors.</div></div>\",\"PeriodicalId\":0,\"journal\":{\"name\":\"\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0,\"publicationDate\":\"2024-09-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"\",\"FirstCategoryId\":\"100\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0378375824000958\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"100","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0378375824000958","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
针对已知相关矩阵的多元正态均值与双侧替代值的同步检验,本文介绍了经证实可对误差发现率进行有限样本控制的新方法。这些方法是通过将每个 p 值向左移动,并根据这些移动的 p 值考虑 Benjamini-Hochberg 型线性阶跃过程而得到的。每个 p 值的移动量可根据相关矩阵适当确定,以实现所需的误发现率控制。模拟研究和实际数据应用表明,与相关竞争者相比,所提出的方法具有良好的性能。
Shifted BH methods for controlling false discovery rate in multiple testing of the means of correlated normals against two-sided alternatives
For simultaneous testing of multivariate normal means with known correlation matrix against two-sided alternatives, this paper introduces new methods with proven finite-sample control of false discovery rate. The methods are obtained by shifting each -value to the left and considering a Benjamini–Hochberg-type linear step-up procedure based on these shifted -values. The amount of shift for each -value is appropriately determined from the correlation matrix to achieve the desired false discovery rate control. Simulation studies and real-data application show favorable performances of the proposed methods when compared with relevant competitors.