[单髁膝关节置换术与无约束和有约束膝关节置换术相比,无菌性翻修的风险明显增加:德国关节置换术登记册对单髁和初级全膝关节置换术后无菌性翻修的分析]。

Orthopadie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-09-23 DOI:10.1007/s00132-024-04561-z
Josina Straub, Dominik Szymski, Nike Walter, Yinan Wu, Oliver Melsheimer, Alexander Grimberg, Volker Alt, Arnd Steinbrück, Markus Rupp
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引用次数: 0

摘要

目的:由于人口老龄化,全膝关节置换术(TKA)的植入率持续上升。初级 TKA 的无菌性翻修是造成翻修的主要原因之一。以下研究旨在确定约束和非约束 TKA 以及单髁膝关节置换术(UKA)中无菌翻修的发生率和原因:方法:在德国关节成形术登记册(EPRD)的帮助下收集数据。无菌翻修手术的原因也以此为依据。无菌翻修手术的发生率和比较采用 Kaplan-Meier 估计法进行分析。采用霍尔姆法进行多重卡方检验,以确定副韧带缺损的组间差异:共分析了 300,998 例膝关节置换术,其中 254,144 例(84.4%)为无约束 TKA,9993 例(3.3%)为有约束 TKA,36,861 例(12.3%)为 UKA。与无约束和有约束 TKA 相比,无菌性翻修的比例明显增加(p 结论:无菌性翻修的比例明显增加:UKA患者的无菌性翻修率明显高于非受限和受限TKA。在无约束 TKA 中,韧带不稳是导致无菌性翻修的最常见原因。在UKA中,胫骨松动是最常见的翻修原因,而骨关节炎的进展则是第二常见的原因。男女患者的韧带不稳定性水平相当: 证据等级:III,队列研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Unicondylar knee arthroplasties demonstrate a significantly increased risk of aseptic revisions compared with unconstrained and constrained TKA : Analysis of aseptic revisions after unicondylar and primary total knee arthroplasty of the German Arthroplasty Register].

Objective: Owing to the ageing population the implantation rate of total knee arthroplasty (TKA) continues to rise. Aseptic revisions in primary TKA are one of the main causes of revision. The aim of the following study was to determine the incidence of and reasons for aseptic revision in constrained and unconstrained TKA and in unicondylar knee arthroplasty (UKA).

Methods: The data collection was carried out with the help of the German Arthroplasty Register (EPRD). The reasons for aseptic revision surgery were worked out using this. The incidence and the comparison of aseptic revisions were analysed with the aid of Kaplan-Meier estimates. A multiple Chi-squared test with the Holm method was used to identify group differences in collateral ligament deficiencies.

Results: In total, 300,998 cases of knee arthroplasties were analysed, of which 254,144 (84.4%) were unconstrained TKA, 9993 (3.3%) were constrained TKA and 36,861 (12.3%) were UKA. The rate of aseptic revisions was significantly increased compared with unconstrained and constrained TKA (p < 0.0001). In constrained TKA, a revision rate of 2.0% for aseptic reasons was reported, whereas in unconstrained TKA 1.1% and in UKA 2.7% revision surgeries were identified. After 7 years the rates of aseptic revisions amounted to 3.3% for constrained TKA, 2.8% for unconstrained TKA and 7.8% for UKA. Ligament instability was the most common cause of aseptic revisions and accounted for 13.7% of unconstrained TKA. In constrained TKA ligament instability led to a revision in 2.8% of cases. In UKA, tibial loosening was identified to be the most common cause of revisions at 14.6%, whereas the progression of osteoarthritis was responsible for 7.9% of revisions. Ligament instability was observed in 14.1% of men compared with 15.9% of women in unconstrained TKA and in UKA in 4.6% of cases for both sexes.

Conclusion: In patients with UKA the rates of aseptic revision are significantly higher than in unconstrained and constrained TKA. Ligament instability was the most common cause of aseptic revision in unconstrained TKA. In UKA, tibial loosening was the most common cause of revision surgery, whereas the progression of osteoarthritis was the second most common cause. Comparable levels of ligament instability were observed in both sexes.

Level of evidence:  III, cohort study.

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