透视硬皮病。

Skinmed Pub Date : 2024-09-17 eCollection Date: 2024-01-01
Alison Romisher, Casey L Ross, Nicholas A Ross
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引用次数: 0

摘要

2 硬皮苔癣是一种慢性炎症性淋巴细胞皮肤病,成人发病率为 1:30 到 1:1,000 不等。3,4 女性患者略占多数,年龄分布呈双峰型,青春期前发病,六七十岁再次发病。研究表明,大多数在青春期前发病的人在成年后仍会患病。5 这种疾病对社会心理的影响,特别是对自我形象、焦虑和性功能的影响,可能会使患者崩溃。治疗的目的是缓解症状和防止进一步的渗出。不幸的是,出现的瘢痕通常是永久性的。10,11 由于目前还不清楚治疗是否会改变恶性变性的理论风险(估计为 4%-5%),12,13 因此需要经常进行临床检查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lichen Sclerosus in Perspective.

Lichen sclerosus (LS) was first described in women by a researcher in 1887.1 It was recognized in men by another investigator in 1928.2 Lichen sclerosus is a chronic, inflammatory lymphocytic dermatosis that occurs in anywhere from 1:30 to 1:1,000 adults.3,4 There is a slight predominance of women, with a bimodal age distribution in pre-pubertal individuals and again in life's sixth-seventh decades. Studies have established that the majority with pre-pubertal onset continue to have adulthood disease.5 Psychosocial implications of this disease, specifically self-image, anxiety, and sexual function, can be debilitating for patients.6-9 As no cure has been described for lichen sclerosus. Treatment is aimed at symptomatic relief and preventing additional effacement. Unfortunately, the scarring that occurs is usually permanent.10,11 As it is unclear whether treatment alters the theoretic risk of malignant degeneration, estimated at 4%-5%,12,13 frequent clinical examinations are indicated.14-17.

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