产妇肥胖的器质性分娩风险:效应大小的估计值。

IF 1.3 Q2 MEDICINE, GENERAL & INTERNAL
Melinda Chai, Amanda Vining, Joseph Koveleskie, William Sumrall, Bobby D Nossaman
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引用次数: 0

摘要

背景:肥胖(定义为体重指数≥30 kg/m2)在美国流行,并与不良事件风险增加有关。有研究探讨了产妇肥胖对器械性阴道分娩发生率的影响,但结果不一。然而,这些分析使用的是频数主义检验,存在错误发现的风险。这项回顾性研究的目的是通过效应大小来量化孕产妇肥胖与工具性分娩需求之间的关联。效应大小测量可评估临床风险因素对相关结果的影响。研究方法2018年1月至2019年5月期间,本院所有年龄≥18岁的待产产妇均纳入本研究。收集并分析患者的人口统计学特征、先前报告的合并症和产科参数,以确定产妇肥胖对器械助产发生率的临床影响。采用风险差异这一效应大小指标来量化产妇肥胖对器械接生需求的临床影响。使用广义线性模型对之前报道的合并症(包括产妇肥胖)的效应大小进行标准化测量,并确定其与器械接生需求的关系。结果显示产妇肥胖的产妇慢性和妊娠高血压、子痫前期、慢性糖尿病和反应性气道疾病的发病率较高。在出现肩难产的产妇中观察到了产妇肥胖造成的风险差异,但在接受催产素诱导的产妇或无阴道的产妇中未观察到这一差异。经过回归分析,产妇肥胖在临床上并不影响对器械助产的需求。结论这些研究结果表明,产妇肥胖对器械助产的临床需求没有影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Risk of Instrumental Delivery in Maternal Obesity: Estimates With Measures of Effect Size.

Background: Obesity, defined as a body mass index ≥30 kg/m2, is epidemic in the United States and is associated with increased risks of adverse events. Studies have examined the role of maternal obesity on the incidence of instrumental vaginal delivery, but the results are divided. However, these analyses used frequentist tests that risk false discovery. The purpose of this retrospective study was to quantify the association of maternal obesity to the need for instrumental delivery with measures of effect size. Measures of effect size allow assessment of the impact of clinical risk factors on outcomes of interest. Methods: All parturients aged ≥18 years in active labor at our facility from January 2018 to May 2019 were entered into this study. Patient demographics, previously reported comorbidities, and obstetric parameters were collected and analyzed to determine the clinical impact of maternal obesity on the incidence of instrumental delivery. One effect size measure, risk differences, was used to quantify the clinical effect of maternal obesity on the need for instrumental delivery. A generalized linear model was used to standardize the measures of effect size of previously reported comorbidities, including maternal obesity, and to determine their association with the need for instrumental delivery. Results: The incidences of chronic and gestational hypertension, preeclampsia, chronic diabetes, and reactive airway disease were higher in parturients with maternal obesity. Risk differences due to maternal obesity were observed in parturients presenting with shoulder dystocia but not in those who underwent oxytocin induction or in nulliparous parturients. Following regression analysis, maternal obesity did not clinically impact the need for instrumental delivery. Conclusion: These findings suggest that maternal obesity did not have a clinical impact on the need for instrumental delivery.

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来源期刊
Ochsner Journal
Ochsner Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
2.10
自引率
0.00%
发文量
71
审稿时长
24 weeks
期刊介绍: The Ochsner Journal is a quarterly publication designed to support Ochsner"s mission to improve the health of our community through a commitment to innovation in healthcare, medical research, and education. The Ochsner Journal provides an active dialogue on practice standards in today"s changing healthcare environment. Emphasis will be given to topics of great societal and medical significance.
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