光子计数计算机断层扫描在冠状动脉成像中的技术原理、优势、挑战和应用:综述。

IF 2.1 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Cardiovascular diagnosis and therapy Pub Date : 2024-08-31 Epub Date: 2024-07-31 DOI:10.21037/cdt-24-52
Antonella Meloni, Erica Maffei, Vincenzo Positano, Alberto Clemente, Carmelo De Gori, Sergio Berti, Ludovico La Grutta, Luca Saba, Eduardo Bossone, Cesare Mantini, Carlo Cavaliere, Bruna Punzo, Simona Celi, Filippo Cademartiri
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引用次数: 0

摘要

背景和目的:光子计数计算机断层扫描(PCCT)的引入代表了临床计算机断层扫描(CT)的最新突破性进展。PCCT 有可能克服传统 CT 的局限性,提供新的定量成像信息。这篇叙述性综述旨在总结 PCCT 的技术原理、优点和挑战,并对 PCCT 在冠状动脉成像领域的应用进行简明而全面的总结:方法:使用相关关键词对 PubMed、Scopus 和 Google Scholar 进行检索,检索时间截止到 2023 年 10 月。主要内容和研究结果:与传统 CT 相比,PCCT 的主要优势在于空间分辨率更高、信号和对比度特性更好、电子噪声和图像伪影更少、辐射量更低、多能量能力更强、材料辨别能力更强。这些关键特性为改进斑块体积和狭窄严重程度的评估、更精确地评估冠状动脉钙化(在减少辐射剂量的情况下也能保留)、改进斑块成分的评估、提供斑块内生物过程细节的可能性、提高冠状动脉支架成像的质量和准确性以及改进放射学分析提供了空间:结论:PCCT 可以极大地影响诊断和临床路径,改善冠状动脉疾病(CAD)患者的管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Technical principles, benefits, challenges, and applications of photon counting computed tomography in coronary imaging: a narrative review.

Background and objective: The introduction of photon-counting computed tomography (PCCT) represents the most recent groundbreaking advancement in clinical computed tomography (CT). PCCT has the potential to overcome the limitations of traditional CT and to provide new quantitative imaging information. This narrative review aims to summarize the technical principles, benefits, and challenges of PCCT and to provide a concise yet comprehensive summary of the applications of PCCT in the domain of coronary imaging.

Methods: A review of PubMed, Scopus, and Google Scholar was performed until October 2023 by using relevant keywords. Articles in English were considered.

Key content and findings: The main advantages of PCCT over traditional CT are enhanced spatial resolution, improved signal and contrast characteristics, diminished electronic noise and image artifacts, lower radiation exposure, and multi-energy capability with enhanced material discrimination. These key characteristics have made room for improved assessment of plaque volume and severity of stenosis, more precise assessment of coronary artery calcifications, also preserved in the case of a reduced radiation dose, improved assessment of plaque composition, possibility to provide details regarding the biological processes occurring within the plaque, enhanced quality and accuracy of coronary stent imaging, and improved radiomic analyses.

Conclusions: PCCT can significantly impact diagnostic and clinical pathways and improve the management of patients with coronary artery diseases (CADs).

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来源期刊
Cardiovascular diagnosis and therapy
Cardiovascular diagnosis and therapy Medicine-Cardiology and Cardiovascular Medicine
CiteScore
4.90
自引率
4.20%
发文量
45
期刊介绍: The journal ''Cardiovascular Diagnosis and Therapy'' (Print ISSN: 2223-3652; Online ISSN: 2223-3660) accepts basic and clinical science submissions related to Cardiovascular Medicine and Surgery. The mission of the journal is the rapid exchange of scientific information between clinicians and scientists worldwide. To reach this goal, the journal will focus on novel media, using a web-based, digital format in addition to traditional print-version. This includes on-line submission, review, publication, and distribution. The digital format will also allow submission of extensive supporting visual material, both images and video. The website www.thecdt.org will serve as the central hub and also allow posting of comments and on-line discussion. The web-site of the journal will be linked to a number of international web-sites (e.g. www.dxy.cn), which will significantly expand the distribution of its contents.
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