髓母细胞瘤患儿的病例系列，描绘了在资源匮乏地区儿童中枢神经系统肿瘤的检测和治疗中存在的护理差异和挑战：乌干达案例研究

IF 3.2 3区医学 Q2 CLINICAL NEUROLOGY

Pediatric neurology Pub Date : 2024-08-23 DOI:10.1016/j.pediatrneurol.2024.08.006

Victoria Katasi Mwebe MBChB, MMED Paediatrics , Emmanuel Wegoye MBChB, MD , Julie Ssekabunga MBChB, MMED Neurosurgery , Justine Onen MBChB, MMED Neurosurgery , Solomon Kibudde MBChB, MMED Internal Medicine , Murali Chintagumpala MBBS, MD , Joseph Lubega MBChB, MD

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引用次数: 0

摘要

背景原发性中枢神经系统肿瘤是高收入国家（HICs）儿童中第二常见的癌症。这些肿瘤也是高收入国家儿童因癌症死亡的主要原因。来自高收入国家的研究报告称，胶质瘤是最常见的儿童癌症。方法：目的是通过一个病例系列，描述低收入国家（LIC）与高收入国家（HIC）相比，中枢神经系统肿瘤患儿在发现、治疗和生存方面的差异。研究人员对乌干达三名接受髓母细胞瘤治疗的儿童进行了回顾性病历审查。结论与高收入国家相比，低收入国家的儿科中枢神经系统肿瘤患儿的治疗质量存在显著差异。在乌干达，这些儿童的管理面临的挑战包括：多学科专家少、距离神经外科中心远、难以做出正确的病理诊断等。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

A Case Series of Children With Medulloblastoma Depicting the Disparities in Care and the Challenges in the Detection and Treatment of Pediatric Central Nervous System Tumors in Low-Resource Settings: A Case Study of Uganda

Background

Primary central nervous system tumors are the second most common cancer among children in high-income countries (HICs). These tumors are also the leading cause of cancer-related deaths in children in this setting. Studies from HICs report gliomas as the most common pediatric cancer. However, there is paucity of data from low- and middle-income countries as not many publications have been made in this field.

Methods

The objective was to describe the disparities in detection, treatment, and survival of children with central nervous system tumors in low-income countries (LICs) when compared with HICs, using a case series. A retrospective chart review of three children treated for medulloblastoma in Uganda was done. In addition, a review of the literature about management of pediatric central nervous system tumors in both LICs and HICs was conducted.

Results

There are no quantifiable results for this case series.

Conclusion

There are notable differences in the quality of care for children with pediatric central nervous system tumors in LICs when compared with HICs. In Uganda, the challenges in management of these children include few multidisciplinary specialists, long distance from the neurosurgery centers, and difficulties in making a correct pathologic diagnosis, among others.

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来源期刊

Pediatric neurology 医学-临床神经学

CiteScore

4.80

自引率

2.60%

发文量

176

审稿时长

78 days

期刊介绍： Pediatric Neurology publishes timely peer-reviewed clinical and research articles covering all aspects of the developing nervous system. Pediatric Neurology features up-to-the-minute publication of the latest advances in the diagnosis, management, and treatment of pediatric neurologic disorders. The journal''s editor, E. Steve Roach, in conjunction with the team of Associate Editors, heads an internationally recognized editorial board, ensuring the most authoritative and extensive coverage of the field. Among the topics covered are: epilepsy, mitochondrial diseases, congenital malformations, chromosomopathies, peripheral neuropathies, perinatal and childhood stroke, cerebral palsy, as well as other diseases affecting the developing nervous system.