{"title":"不可忽视的炎症","authors":"Hany Ariffin","doi":"10.1111/bjh.19773","DOIUrl":null,"url":null,"abstract":"Haemophagocytic lymphohistiocytosis (HLH) that occurs concomitantly with leukaemia can be initially missed due to overlapping clinical features. In a series of three cases, Tanabe and colleagues illustrate the need for prompt recognition of HLH and institution of HLH‐directed therapy to prevent hyperinflammation‐mediated multi‐organ damage and death.Commentary on: Tanabe et al. Paediatric acute lymphoblastic leukaemia‐associated haemophagocytic lymphohistiocytosis develops during prednisolone prephase. Br J Haematol 2024 (Online ahead of print). doi: <jats:ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"https://doi.org/10.1111/bjh.19755\">10.1111/bjh.19755</jats:ext-link>.","PeriodicalId":135,"journal":{"name":"British Journal of Haematology","volume":null,"pages":null},"PeriodicalIF":5.1000,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Incorrigible inflammation\",\"authors\":\"Hany Ariffin\",\"doi\":\"10.1111/bjh.19773\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Haemophagocytic lymphohistiocytosis (HLH) that occurs concomitantly with leukaemia can be initially missed due to overlapping clinical features. In a series of three cases, Tanabe and colleagues illustrate the need for prompt recognition of HLH and institution of HLH‐directed therapy to prevent hyperinflammation‐mediated multi‐organ damage and death.Commentary on: Tanabe et al. Paediatric acute lymphoblastic leukaemia‐associated haemophagocytic lymphohistiocytosis develops during prednisolone prephase. Br J Haematol 2024 (Online ahead of print). doi: <jats:ext-link xmlns:xlink=\\\"http://www.w3.org/1999/xlink\\\" xlink:href=\\\"https://doi.org/10.1111/bjh.19755\\\">10.1111/bjh.19755</jats:ext-link>.\",\"PeriodicalId\":135,\"journal\":{\"name\":\"British Journal of Haematology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":5.1000,\"publicationDate\":\"2024-09-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British Journal of Haematology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/bjh.19773\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"HEMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British Journal of Haematology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/bjh.19773","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEMATOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
与白血病同时发生的嗜血细胞淋巴组织细胞增多症(HLH)最初可能因临床特征重叠而被漏诊。Tanabe及其同事在三个病例中说明了及时识别HLH并进行HLH定向治疗的必要性,以防止高炎症介导的多器官损伤和死亡:Tanabe等人.儿科急性淋巴细胞白血病相关嗜血细胞淋巴组织细胞增多症在泼尼松龙前期发展.Br J Haematol 2024 (Online ahead of print). doi: 10.1111/bjh.19755.
Haemophagocytic lymphohistiocytosis (HLH) that occurs concomitantly with leukaemia can be initially missed due to overlapping clinical features. In a series of three cases, Tanabe and colleagues illustrate the need for prompt recognition of HLH and institution of HLH‐directed therapy to prevent hyperinflammation‐mediated multi‐organ damage and death.Commentary on: Tanabe et al. Paediatric acute lymphoblastic leukaemia‐associated haemophagocytic lymphohistiocytosis develops during prednisolone prephase. Br J Haematol 2024 (Online ahead of print). doi: 10.1111/bjh.19755.
期刊介绍:
The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.