抑郁症的肠脑轴：多组学是否指明了方向？

IF 11.7 1区医学 Q1 CELL BIOLOGY

Cell Reports Medicine Pub Date : 2024-09-17 DOI:10.1016/j.xcrm.2024.101741

Jane Allyson Foster, Madhukar Hariprasad Trivedi

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引用次数: 0

摘要

现在是精神病学范式转变的时候了。人们越来越需要基于生物学的模型来了解临床异质性。将微生物组纳入生物标志物的发现，提供了一种易于使用的生物方法，以产生与临床相关的生物标志物，全面考虑宿主和环境。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The gut-brain axis in depression: Are multi-omics showing the way?

It is time for a paradigm shift in psychiatry. The need for biologically based models to understand clinical heterogeneity is gaining momentum. Integrating the microbiome into biomarker discovery provides an accessible, biological approach to generate clinically relevant biomarkers that consider the host and the environment in a comprehensive way.

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来源期刊

Cell Reports Medicine Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

15.00

自引率

1.40%

发文量

231

审稿时长

40 days

期刊介绍： Cell Reports Medicine is an esteemed open-access journal by Cell Press that publishes groundbreaking research in translational and clinical biomedical sciences, influencing human health and medicine. Our journal ensures wide visibility and accessibility, reaching scientists and clinicians across various medical disciplines. We publish original research that spans from intriguing human biology concepts to all aspects of clinical work. We encourage submissions that introduce innovative ideas, forging new paths in clinical research and practice. We also welcome studies that provide vital information, enhancing our understanding of current standards of care in diagnosis, treatment, and prognosis. This encompasses translational studies, clinical trials (including long-term follow-ups), genomics, biomarker discovery, and technological advancements that contribute to diagnostics, treatment, and healthcare. Additionally, studies based on vertebrate model organisms are within the scope of the journal, as long as they directly relate to human health and disease.