揭示配体 M1069 与人血清白蛋白和 A2A 腺苷受体的结合相互作用机制--一种生物物理方法

IF 2.4 3区化学 Q2 CHEMISTRY, ORGANIC

Polycyclic Aromatic Compounds Pub Date : 2024-09-09 DOI:10.1080/10406638.2024.2399536

Shajith Ahamed Azees, Rupavarshini Manoharan, Navaneeth Alanthata Govindan, Bernet Shano Leon, Karthikeyan Subramani

引用次数: 0

摘要

这项研究的重点是M1069，它是一种治疗实体瘤的有前途的药物，具有A2A腺苷受体拮抗剂的功能。在本研究中，我们通过采用...

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Insight into the Binding Interaction Mechanism of the Ligand M1069 with Human Serum Albumin and A2A Adenosine Receptor—A Biophysical Approach

The study focuses on M1069, a promising drug for solid tumors functioning as an A2A adenosine receptor antagonist. Herein, we investigate the binding mechanism of the drug molecule M1069 by employi...

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来源期刊

Polycyclic Aromatic Compounds 化学-有机化学

CiteScore

3.70

自引率

20.80%

发文量

412

审稿时长

3 months

期刊介绍： The purpose of Polycyclic Aromatic Compounds is to provide an international and interdisciplinary forum for all aspects of research related to polycyclic aromatic compounds (PAC). Topics range from fundamental research in chemistry (including synthetic and theoretical chemistry) and physics (including astrophysics), as well as thermodynamics, spectroscopy, analytical methods, and biology to applied studies in environmental science, biochemistry, toxicology, and industry. Polycyclic Aromatic Compounds has an outstanding Editorial Board and offers a rapid and efficient peer review process, as well as a flexible open access policy.