Santiago Ferrière-Steinert,Maximiliano Acevedo de la Barra,Alexandra Neman,Tamara Vergara Cerón,Rodrigo A Cornejo,Abraham I Vn J Gajardo
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引用次数: 0
摘要
Kang 等人就延长俯卧位对插管 COVID-19 ARDS 患者的影响所做的系统综述和荟萃分析提供了有关延长俯卧位有效性和安全性的宝贵发现,但也提出了一些需要澄清的问题。该研究纳入了没有对照组的观察性研究、使用了观察性研究中关键变量的粗略估计值而非调整估计值、随机临床试验数据提取错误以及使用了几率比而非风险比,这些都可能误导对上述干预措施的解释。
Effect of Extended Prone Positioning in Intubated COVID-19 Patients with Acute Respiratory Distress Syndrome, a Revision Letter.
The systematic review and meta-analysis performed by Kang et al about the effect of extended prone positioning in intubated COVID-19 patients with ARDS presents valuable findings on the effectiveness and safety of extended prone positioning, but also raises several concerns which require clarifications. The inclusion of observational studies without any control group, the use of crude rather than adjusted estimates in key variables from observational studies, an error in data extraction from randomized clinical trials, and the employment of odds ratios rather than risk ratios, may mislead interpretations of the aforementioned intervention.
期刊介绍:
Journal of Intensive Care Medicine (JIC) is a peer-reviewed bi-monthly journal offering medical and surgical clinicians in adult and pediatric intensive care state-of-the-art, broad-based analytic reviews and updates, original articles, reports of large clinical series, techniques and procedures, topic-specific electronic resources, book reviews, and editorials on all aspects of intensive/critical/coronary care.