儿童患者心房颤动的患病率、管理和疗效:来自三级心脏病学中心的启示

Q4 Medicine
Medicina Pub Date : 2024-09-15 DOI:10.3390/medicina60091505
Andreia Duarte Constante, Joana Suarez, Guilherme Lourenço, Guilherme Portugal, Pedro Silva Cunha, Mário Martins Oliveira, Conceição Trigo, Fátima F. Pinto, Sérgio Laranjo
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引用次数: 0

摘要

背景和目的:房颤(AF)在儿科患者中的发病率越来越高,由于其与各种潜在的心脏疾病相关,因此在管理上面临着独特的挑战。本研究旨在评估房颤在这一人群中的患病率、管理策略和治疗效果。材料和方法:在一家三级儿科心脏病学中心进行了一项回顾性分析,研究对象包括 2015 年 1 月至 2023 年 12 月期间确诊为房颤的 18 岁以下患者。研究侧重于人口统计学细节、临床表现、治疗和结果。研究采用描述性统计来评估治疗效果、复发率和并发症。研究结果研究共纳入 36 名儿童患者(中位年龄:15 岁,IQR:13-17 岁;58% 为男性)。其中,52.8%患有后天性心脏病,16.7%患有先天性心脏畸形,16.7%为单发房颤。53.3%的患者采用电复律治疗,46.7%的患者采用胺碘酮药物治疗。超过80%的患者接受了节律控制治疗,63.9%的患者接受了口服抗凝治疗,主要用于治疗风湿性和先天性心脏病。心律控制的总体成功率为 96.2%,房颤复发率为 3.8%。缺血性中风是最常见的并发症,有三名患者发生了这种并发症,他们都患有潜在的风湿性心脏病。结论儿科房颤主要与风湿性心脏病和先天性心脏病有关,但也有相当一部分患者表现为单独房颤。尽管大多数病例都能有效控制心律,但神经系统并发症,尤其是有潜在心脏病的患者发生缺血性中风,仍然是一个令人严重关切的问题。这些发现强调了进行更全面研究的必要性,以便更好地了解小儿房颤的病因、风险因素和最佳管理策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence, Management, and Outcomes of Atrial Fibrillation in Paediatric Patients: Insights from a Tertiary Cardiology Centre
Background and Objectives: Atrial fibrillation (AF) is increasingly recognised in paediatric patients, presenting unique challenges in management due to its association with various underlying heart conditions. This study aimed to evaluate the prevalence, management strategies, and outcomes of AF in this population. Materials and Methods: A retrospective analysis was conducted at a tertiary paediatric cardiology centre, including patients aged ≤18 years diagnosed with AF between January 2015 and December 2023. The study focused on demographic details, clinical presentations, treatments, and outcomes. Descriptive statistics were employed to assess treatment efficacy, recurrence rates, and complications. Results: The study included 36 paediatric patients (median age: 15 years, IQR: 13–17; 58% male). Of these, 52.8% had acquired heart disease, 16.7% had congenital heart anomalies, and 16.7% presented with lone AF. The initial management strategies involved electrical cardioversion in 53.3% of patients and pharmacological conversion with amiodarone in 46.7%. Rhythm control therapy was administered to over 80% of the cohort, and 63.9% were placed on oral anticoagulation, predominantly for rheumatic and congenital heart diseases. The overall success rate of rhythm control was 96.2%, with an AF recurrence rate of 3.8%. Ischemic stroke was the most common complication, occurring in three patients, all with underlying rheumatic heart disease. Conclusions: AF in paediatric patients is predominantly associated with rheumatic and congenital heart diseases, though a significant proportion of patients present with lone AF. Despite effective rhythm control in most cases, neurological complications, particularly ischemic strokes in patients with underlying heart disease, remain a critical concern. These findings underscore the need for more comprehensive studies to better understand the aetiology, risk factors, and optimal management strategies for paediatric AF.
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来源期刊
Medicina
Medicina Medicine-Medicine (all)
CiteScore
0.10
自引率
0.00%
发文量
66
审稿时长
24 weeks
期刊介绍: Publicada con el apoyo del Ministerio de Ciencia, Tecnología e Innovación Productiva. Medicina no tiene propósitos comerciales. El objeto de su creación ha sido propender al adelanto de la medicina argentina. Los beneficios que pudieran obtenerse serán aplicados exclusivamente a ese fin.
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