与交通有关的空气和噪音污染对老年人过敏性疾病的影响:一项观察性研究。

IF 4.9 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Sofia Tagliaferro,Federico Pirona,Salvatore Fasola,Ilaria Stanisci,Giuseppe Sarno,Sandra Baldacci,Claudio Gariazzo,Gaetano Licitra,Antonino Moro,Camillo Silibello,Massimo Stafoggia,Giovanni Viegi,Sara Maio,,,
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引用次数: 0

摘要

引言与交通有关的空气和噪音污染是重要的公共健康问题。本研究旨在估算它们对成年和老年受试者过敏/呼吸系统结果的影响。材料和方法通过对居住在比萨(意大利托斯卡纳区)的 645 名受试者进行过敏/呼吸系统症状和疾病问卷调查。通过问卷调查、模拟二氧化氮年平均浓度(1 公里和 200 米分辨率)以及 24 小时内的噪音水平(Lden),对居住地址的交通相关空气污染和噪音暴露进行了评估。暴露影响通过逻辑回归模型进行评估,该模型按年龄组(18-64 岁,≥65 岁)分层,并根据性别、教育水平、职业暴露和吸烟习惯进行调整。平均暴露水平为在分辨率为 200 米和 1 千米的地方,二氧化氮的平均暴露水平分别为 28.24 微克/立方米(±3.26 标度)和 27.23 微克/立方米(±3.16 标度);臭氧浓度为 57.79 分贝(A)(±6.12 标度)。仅在老年人中,暴露于车辆交通(通过问卷调查)和高噪音水平[Lden ≥ 60 dB(A)]与较高的过敏性鼻炎几率(OR 分别为 2.01,95%CI 1.09-3.70;OR 分别为 1.99,95%CI 1.18-3.36)和边缘性鼻结膜炎(OR 分别为 2.20,95%CI 0.95-5.10;OR 分别为 1.76,95%CI 0.91-3.42)显著相关。结论考虑到未来全球人口老龄化趋势的加剧,我们的研究结果突出表明有必要更好地评估交通相关暴露对老年人的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of traffic-related air and noise pollution exposure on allergic diseases in the elderly: an observational study.
INTRODUCTION Traffic-related air and noise pollution are important public health issues. The aim of this study was to estimate their effects on allergic/respiratory outcomes in adult and elderly subjects. MATERIALS AND METHODS Six hundred and forty-five subjects living in Pisa (Tuscany, Italy) were investigated through a questionnaire on allergic/respiratory symptoms and diseases. Traffic-related air pollution and noise exposures were assessed at residential address by questionnaire, modelled annual mean NO2 concentrations (1 km and 200 m resolution), and noise level over a 24-h period (Lden). Exposure effects were assessed through logistic regression models stratified by age group (18-64 years, ≥65 years), and adjusted for sex, educational level, occupational exposure, and smoking habits. RESULTS 63.6% of the subjects reported traffic exposure near home. Mean exposure levels were: 28.24 (±3.26 SD) and 27.23 (±3.16 SD) µg/m3 for NO2 at 200 m and 1 km of resolution, respectively; 57.79 dB(A) (±6.12 SD) for Lden. Exposure to vehicular traffic (by questionnaire) and to high noise levels [Lden ≥ 60 dB(A)] were significantly associated with higher odds of allergic rhinitis (OR 2.01, 95%CI 1.09-3.70, and OR 1.99, 95%CI 1.18-3.36, respectively) and borderline with rhino-conjunctivitis (OR 2.20, 95%CI 0.95-5.10, and OR 1.76, 95%CI 0.91-3.42, respectively) only in the elderly. No significant result emerged for NO2. CONCLUSIONS Our findings highlighted the need to better assess the effect of traffic-related exposure in the elderly, considering the increasing trend in the future global population's ageing.
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来源期刊
Annals of medicine
Annals of medicine 医学-医学:内科
CiteScore
4.90
自引率
0.00%
发文量
292
审稿时长
3 months
期刊介绍: Annals of Medicine is one of the world’s leading general medical review journals, boasting an impact factor of 5.435. It presents high-quality topical review articles, commissioned by the Editors and Editorial Committee, as well as original articles. The journal provides the current opinion on recent developments across the major medical specialties, with a particular focus on internal medicine. The peer-reviewed content of the journal keeps readers updated on the latest advances in the understanding of the pathogenesis of diseases, and in how molecular medicine and genetics can be applied in daily clinical practice.
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