{"title":"急诊科功能性神经紊乱简介","authors":"Melanie Eden BBiomedSci (Hons), MD","doi":"10.1111/1742-6723.14492","DOIUrl":null,"url":null,"abstract":"<p>Functional neurological disorders (FNDs) are conditions of nervous system malfunctioning, rather than a clearly identifiable pathophysiological disease.<span><sup>1</sup></span> FND can present with an array of symptoms, including functional seizures, weakness and paralysis, movement disorders, speech disturbances, globus sensation, sensory complaints, visual and cognitive symptoms. These symptoms may be acute or chronic, episodic or sustained and patients often have a high rate of representation to the ED.<span><sup>2</sup></span> These factors make FND a challenge to manage within the constraints of the ED.</p><p>Previously, FND was considered a diagnosis of exclusion. Recently, FND has been described as a ‘rule-in’ diagnosis, with positive findings offering the possibility of early diagnosis and management in the ED. Shorter time from symptom onset to diagnosis is an important positive prognostic factor, leading to reduced ED utilisation and improved patient outcomes.<span><sup>3</sup></span></p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1742-6723.14492","citationCount":"0","resultStr":"{\"title\":\"An introduction to functional neurological disorders in the emergency department\",\"authors\":\"Melanie Eden BBiomedSci (Hons), MD\",\"doi\":\"10.1111/1742-6723.14492\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Functional neurological disorders (FNDs) are conditions of nervous system malfunctioning, rather than a clearly identifiable pathophysiological disease.<span><sup>1</sup></span> FND can present with an array of symptoms, including functional seizures, weakness and paralysis, movement disorders, speech disturbances, globus sensation, sensory complaints, visual and cognitive symptoms. These symptoms may be acute or chronic, episodic or sustained and patients often have a high rate of representation to the ED.<span><sup>2</sup></span> These factors make FND a challenge to manage within the constraints of the ED.</p><p>Previously, FND was considered a diagnosis of exclusion. Recently, FND has been described as a ‘rule-in’ diagnosis, with positive findings offering the possibility of early diagnosis and management in the ED. Shorter time from symptom onset to diagnosis is an important positive prognostic factor, leading to reduced ED utilisation and improved patient outcomes.<span><sup>3</sup></span></p>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1742-6723.14492\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/1742-6723.14492\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/1742-6723.14492","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
An introduction to functional neurological disorders in the emergency department
Functional neurological disorders (FNDs) are conditions of nervous system malfunctioning, rather than a clearly identifiable pathophysiological disease.1 FND can present with an array of symptoms, including functional seizures, weakness and paralysis, movement disorders, speech disturbances, globus sensation, sensory complaints, visual and cognitive symptoms. These symptoms may be acute or chronic, episodic or sustained and patients often have a high rate of representation to the ED.2 These factors make FND a challenge to manage within the constraints of the ED.
Previously, FND was considered a diagnosis of exclusion. Recently, FND has been described as a ‘rule-in’ diagnosis, with positive findings offering the possibility of early diagnosis and management in the ED. Shorter time from symptom onset to diagnosis is an important positive prognostic factor, leading to reduced ED utilisation and improved patient outcomes.3
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.