将土耳其植物区系中的互叶紫草的化学特征与生物活性联系起来

IF 4 2区化学 Q2 CHEMISTRY, PHYSICAL

Journal of Molecular Structure Pub Date : 2024-09-13 DOI:10.1016/j.molstruc.2024.140052

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引用次数: 0

摘要

研究了使用不同极性溶剂（正己烷、乙酸乙酯、二氯甲烷、甲醇和水）获得的五种互叶紫草提取物的化学成分和体外生物活性。LC-MSn 分析表明，受检植物材料中存在酚酸衍生物、类黄酮、单宁和花青素等生物活性分子，其中甲醇提取物中的生物活性分子最多。生物活性通过抗氧化、酶抑制剂和细胞毒性实验进行了体外评估。提取物具有显著的生物潜力，其中甲醇提取物最为有效。分析提取物表明，这种随手可得的原材料是植物营养素（主要是抗氧化化合物）的丰富来源。这项研究使人们对土耳其红豆杉提取物的未来前景产生了好奇，因为它可用于配制新产品作为营养补充剂或提高现有产品的质量。这些潜在的应用为未来天然产品的开发及其对人类健康的影响带来了希望。

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Linking the chemical profile with the biological activities of Reaumuria alternifolia from Turkish flora

The chemical composition and in vitro bioactivity of five Reaumuria alternifolia extracts obtained using solvents of different polarities (hexane, ethyl acetate, dichloromethane, methanol, and water) were investigated. LC-MSⁿ analysis revealed the presence of phenolic acid derivatives, flavonoids, tannins, and anthocyanins as bioactive molecules in the examined plant material, the majority identified in the methanol extract. Bioactivity was evaluated in vitro through antioxidant, enzyme inhibitor, and cytotoxic assays. Extracts presented a significant biological potential, with the methanol extract being the most effective. The analyzed extracts showed that this readily available raw material is a rich source of phytonutrients, primarily antioxidant compounds. This research raises curiosity about the future perspective of Turkish Reaumuria alternifolia extracts, for the formulation of new products as nutritional supplements or improving the quality of existing products. These potential applications inspire hope for the future of natural product development and its impact on human health.

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来源期刊

Journal of Molecular Structure 化学-物理化学

CiteScore

7.10

自引率

15.80%

发文量

2384

审稿时长

45 days

期刊介绍： The Journal of Molecular Structure is dedicated to the publication of full-length articles and review papers, providing important new structural information on all types of chemical species including: • Stable and unstable molecules in all types of environments (vapour, molecular beam, liquid, solution, liquid crystal, solid state, matrix-isolated, surface-absorbed etc.) • Chemical intermediates • Molecules in excited states • Biological molecules • Polymers. The methods used may include any combination of spectroscopic and non-spectroscopic techniques, for example: • Infrared spectroscopy (mid, far, near) • Raman spectroscopy and non-linear Raman methods (CARS, etc.) • Electronic absorption spectroscopy • Optical rotatory dispersion and circular dichroism • Fluorescence and phosphorescence techniques • Electron spectroscopies (PES, XPS), EXAFS, etc. • Microwave spectroscopy • Electron diffraction • NMR and ESR spectroscopies • Mössbauer spectroscopy • X-ray crystallography • Charge Density Analyses • Computational Studies (supplementing experimental methods) We encourage publications combining theoretical and experimental approaches. The structural insights gained by the studies should be correlated with the properties, activity and/ or reactivity of the molecule under investigation and the relevance of this molecule and its implications should be discussed.