{"title":"作为青光眼诊断标志的红细胞渗透脆性：使用 LASSO 回归进行综合分析","authors":"Jialiang Yang, Fang Yang, Junming Gu, Yilian Cheng, Qian Luo, Fang Hao, Bo Gong, Houbin Zhang","doi":"10.1101/2024.09.05.24312988","DOIUrl":null,"url":null,"abstract":"<strong>Objective</strong> This study investigates the potential of blood biomarkers in the early diagnosis of glaucoma, focusing on erythrocyte osmotic fragility (EOF) as a novel indicator. We used Least Absolute Shrinkage and Selection Operator (LASSO) regression to evaluate EOF’s predictive utility for glaucoma diagnosis.","PeriodicalId":501390,"journal":{"name":"medRxiv - Ophthalmology","volume":"59 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Erythrocyte Osmotic Fragility as A Diagnostic Marker in Glaucoma: A Comprehensive Analysis Using LASSO Regression\",\"authors\":\"Jialiang Yang, Fang Yang, Junming Gu, Yilian Cheng, Qian Luo, Fang Hao, Bo Gong, Houbin Zhang\",\"doi\":\"10.1101/2024.09.05.24312988\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<strong>Objective</strong> This study investigates the potential of blood biomarkers in the early diagnosis of glaucoma, focusing on erythrocyte osmotic fragility (EOF) as a novel indicator. We used Least Absolute Shrinkage and Selection Operator (LASSO) regression to evaluate EOF’s predictive utility for glaucoma diagnosis.\",\"PeriodicalId\":501390,\"journal\":{\"name\":\"medRxiv - Ophthalmology\",\"volume\":\"59 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.09.05.24312988\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.09.05.24312988","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Erythrocyte Osmotic Fragility as A Diagnostic Marker in Glaucoma: A Comprehensive Analysis Using LASSO Regression
Objective This study investigates the potential of blood biomarkers in the early diagnosis of glaucoma, focusing on erythrocyte osmotic fragility (EOF) as a novel indicator. We used Least Absolute Shrinkage and Selection Operator (LASSO) regression to evaluate EOF’s predictive utility for glaucoma diagnosis.
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