作为青光眼诊断标志的红细胞渗透脆性：使用 LASSO 回归进行综合分析

medRxiv - Ophthalmology Pub Date : 2024-09-06 DOI:10.1101/2024.09.05.24312988

Jialiang Yang, Fang Yang, Junming Gu, Yilian Cheng, Qian Luo, Fang Hao, Bo Gong, Houbin Zhang

{"title":"作为青光眼诊断标志的红细胞渗透脆性：使用 LASSO 回归进行综合分析","authors":"Jialiang Yang, Fang Yang, Junming Gu, Yilian Cheng, Qian Luo, Fang Hao, Bo Gong, Houbin Zhang","doi":"10.1101/2024.09.05.24312988","DOIUrl":null,"url":null,"abstract":"<strong>Objective</strong> This study investigates the potential of blood biomarkers in the early diagnosis of glaucoma, focusing on erythrocyte osmotic fragility (EOF) as a novel indicator. We used Least Absolute Shrinkage and Selection Operator (LASSO) regression to evaluate EOF’s predictive utility for glaucoma diagnosis.","PeriodicalId":501390,"journal":{"name":"medRxiv - Ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Erythrocyte Osmotic Fragility as A Diagnostic Marker in Glaucoma: A Comprehensive Analysis Using LASSO Regression\",\"authors\":\"Jialiang Yang, Fang Yang, Junming Gu, Yilian Cheng, Qian Luo, Fang Hao, Bo Gong, Houbin Zhang\",\"doi\":\"10.1101/2024.09.05.24312988\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<strong>Objective</strong> This study investigates the potential of blood biomarkers in the early diagnosis of glaucoma, focusing on erythrocyte osmotic fragility (EOF) as a novel indicator. We used Least Absolute Shrinkage and Selection Operator (LASSO) regression to evaluate EOF’s predictive utility for glaucoma diagnosis.\",\"PeriodicalId\":501390,\"journal\":{\"name\":\"medRxiv - Ophthalmology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.09.05.24312988\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.09.05.24312988","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

目的本研究探讨了血液生物标志物在青光眼早期诊断中的潜力，重点研究了红细胞渗透脆性（EOF）这一新型指标。我们采用最小绝对收缩和选择操作器（LASSO）回归法来评估 EOF 对青光眼诊断的预测作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Erythrocyte Osmotic Fragility as A Diagnostic Marker in Glaucoma: A Comprehensive Analysis Using LASSO Regression

Objective This study investigates the potential of blood biomarkers in the early diagnosis of glaucoma, focusing on erythrocyte osmotic fragility (EOF) as a novel indicator. We used Least Absolute Shrinkage and Selection Operator (LASSO) regression to evaluate EOF’s predictive utility for glaucoma diagnosis.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

medRxiv - Ophthalmology

自引率

0.00%

发文量