基于胶原蛋白和羧甲基纤维素的复合凝胶的结构和稳定性

IF 1.1 4区物理与天体物理 Q4 PHYSICS, APPLIED

Technical Physics Pub Date : 2024-09-02 DOI:10.1134/s1063784224010298

Y. A. Nashchekina, V. A. Konson, M. Y. Sirotkina, A. V. Nashchekin

{"title":"基于胶原蛋白和羧甲基纤维素的复合凝胶的结构和稳定性","authors":"Y. A. Nashchekina, V. A. Konson, M. Y. Sirotkina, A. V. Nashchekin","doi":"10.1134/s1063784224010298","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The creation of biocompatible gels, based on type I collagen is studied. To improve the mechanical properties, 10–30% carboxymethylcellulose (CMC) was added to the collagen gel. It is shown that with an increase in the CMC content up to 30%, the stability of composite gels increases. With the help of scanning electron microscopy it is shown, that the ability of collagen to form native fibrils decreases with the addition of CMC. It was also shown by electrophoresis that the presence of CMC increases the rate of degradation of the composite collagen gel.</p>","PeriodicalId":783,"journal":{"name":"Technical Physics","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Structure and Stability of Composite Gels Based on Collagen and Carboxymethylcellulose\",\"authors\":\"Y. A. Nashchekina, V. A. Konson, M. Y. Sirotkina, A. V. Nashchekin\",\"doi\":\"10.1134/s1063784224010298\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<h3 data-test=\\\"abstract-sub-heading\\\">Abstract</h3><p>The creation of biocompatible gels, based on type I collagen is studied. To improve the mechanical properties, 10–30% carboxymethylcellulose (CMC) was added to the collagen gel. It is shown that with an increase in the CMC content up to 30%, the stability of composite gels increases. With the help of scanning electron microscopy it is shown, that the ability of collagen to form native fibrils decreases with the addition of CMC. It was also shown by electrophoresis that the presence of CMC increases the rate of degradation of the composite collagen gel.</p>\",\"PeriodicalId\":783,\"journal\":{\"name\":\"Technical Physics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2024-09-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Technical Physics\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://doi.org/10.1134/s1063784224010298\",\"RegionNum\":4,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHYSICS, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Technical Physics","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1134/s1063784224010298","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHYSICS, APPLIED","Score":null,"Total":0}

引用次数: 0

摘要

摘要研究了基于 I 型胶原蛋白的生物相容性凝胶。为了改善机械性能，在胶原蛋白凝胶中添加了 10-30% 的羧甲基纤维素（CMC）。研究表明，随着 CMC 含量增加到 30%，复合凝胶的稳定性也会增加。扫描电子显微镜显示，添加 CMC 后，胶原蛋白形成原生纤维的能力下降。电泳也表明，CMC 的存在会增加复合胶原凝胶的降解率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Structure and Stability of Composite Gels Based on Collagen and Carboxymethylcellulose

查看原文本刊更多论文

Structure and Stability of Composite Gels Based on Collagen and Carboxymethylcellulose

Abstract

The creation of biocompatible gels, based on type I collagen is studied. To improve the mechanical properties, 10–30% carboxymethylcellulose (CMC) was added to the collagen gel. It is shown that with an increase in the CMC content up to 30%, the stability of composite gels increases. With the help of scanning electron microscopy it is shown, that the ability of collagen to form native fibrils decreases with the addition of CMC. It was also shown by electrophoresis that the presence of CMC increases the rate of degradation of the composite collagen gel.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Technical Physics 物理-物理：应用

CiteScore

1.30

自引率

14.30%

发文量

139

审稿时长

3-6 weeks

期刊介绍： Technical Physics is a journal that contains practical information on all aspects of applied physics, especially instrumentation and measurement techniques. Particular emphasis is put on plasma physics and related fields such as studies of charged particles in electromagnetic fields, synchrotron radiation, electron and ion beams, gas lasers and discharges. Other journal topics are the properties of condensed matter, including semiconductors, superconductors, gases, liquids, and different materials.