{"title":"增强心肌梗死诊断:基于 LSTM 的深度学习方法与超声心动图室壁运动分析相结合","authors":"Hsu Thiri Soe, Hiroyasu Iwata","doi":"10.1007/s40846-024-00897-1","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Owing to the increased mortality of heart diseases worldwide, especially myocardial infarction (MI), early detection is essential for improved diagnosis and treatment. The main purpose of this study is to develop a myocardial infarction detection method that combines deep learning and image processing, focusing on abnormalities in left ventricular (LV) wall motion.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>The proposed method primarily uses the LV wall motion movement as a feature to train an LSTM network for MI detection. LV wall motion annotated by expert cardiologists was used as the ground truth. Accuracy, sensitivity, specificity, and area under the curve (AUC) were used to evaluate model performance. The proposed method primarily uses LV wall motion as a feature, combined with LV size and image pixels, to improve diagnostic accuracy over existing computer-aided design (CAD) systems.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>The LSTM model achieved the highest diagnostic performance when trained on a combination of LV wall motion, LV size, and image pixel features with an accuracy of 95%, sensitivity of 96%, specificity of 94%, and an AUC value of 0.98. The LSTM model significantly outperformed models trained on individual feature sets or conventional machine learning algorithms. The inclusion of LV wall motion analysis improved accuracy by 10% compared to using only LV size and pixel data.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Our MI diagnosis system uses echocardiographic image analysis and LSTM-based deep learning to accurately detect LV wall motion issues related to MI. Compared with current CAD systems, the inclusion of LV wall motion analysis significantly improves diagnosis accuracy. The proposed system can help physicians detect MI early, thereby accelerating treatment and improving patient outcomes.</p>","PeriodicalId":50133,"journal":{"name":"Journal of Medical and Biological Engineering","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enhancing Myocardial Infarction Diagnosis: LSTM-based Deep Learning Approach Integrating Echocardiographic Wall Motion Analysis\",\"authors\":\"Hsu Thiri Soe, Hiroyasu Iwata\",\"doi\":\"10.1007/s40846-024-00897-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<h3 data-test=\\\"abstract-sub-heading\\\">Purpose</h3><p>Owing to the increased mortality of heart diseases worldwide, especially myocardial infarction (MI), early detection is essential for improved diagnosis and treatment. The main purpose of this study is to develop a myocardial infarction detection method that combines deep learning and image processing, focusing on abnormalities in left ventricular (LV) wall motion.</p><h3 data-test=\\\"abstract-sub-heading\\\">Methods</h3><p>The proposed method primarily uses the LV wall motion movement as a feature to train an LSTM network for MI detection. LV wall motion annotated by expert cardiologists was used as the ground truth. Accuracy, sensitivity, specificity, and area under the curve (AUC) were used to evaluate model performance. The proposed method primarily uses LV wall motion as a feature, combined with LV size and image pixels, to improve diagnostic accuracy over existing computer-aided design (CAD) systems.</p><h3 data-test=\\\"abstract-sub-heading\\\">Results</h3><p>The LSTM model achieved the highest diagnostic performance when trained on a combination of LV wall motion, LV size, and image pixel features with an accuracy of 95%, sensitivity of 96%, specificity of 94%, and an AUC value of 0.98. The LSTM model significantly outperformed models trained on individual feature sets or conventional machine learning algorithms. The inclusion of LV wall motion analysis improved accuracy by 10% compared to using only LV size and pixel data.</p><h3 data-test=\\\"abstract-sub-heading\\\">Conclusion</h3><p>Our MI diagnosis system uses echocardiographic image analysis and LSTM-based deep learning to accurately detect LV wall motion issues related to MI. Compared with current CAD systems, the inclusion of LV wall motion analysis significantly improves diagnosis accuracy. The proposed system can help physicians detect MI early, thereby accelerating treatment and improving patient outcomes.</p>\",\"PeriodicalId\":50133,\"journal\":{\"name\":\"Journal of Medical and Biological Engineering\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2024-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical and Biological Engineering\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1007/s40846-024-00897-1\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical and Biological Engineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1007/s40846-024-00897-1","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
摘要
目的随着全球心脏病死亡率的上升,尤其是心肌梗塞(MI),早期检测对于改善诊断和治疗至关重要。本研究的主要目的是开发一种结合深度学习和图像处理的心肌梗塞检测方法,重点关注左心室壁运动异常。由心脏病专家标注的左心室壁运动作为基本事实。准确度、灵敏度、特异性和曲线下面积(AUC)用于评估模型性能。与现有的计算机辅助设计(CAD)系统相比,所提出的方法主要以左心室壁运动为特征,并结合左心室大小和图像像素,以提高诊断准确率。LSTM 模型的表现明显优于根据单个特征集或传统机器学习算法训练的模型。结论我们的 MI 诊断系统使用超声心动图图像分析和基于 LSTM 的深度学习来准确检测与 MI 相关的左心室壁运动问题。与当前的 CAD 系统相比,加入左心室壁运动分析可显著提高诊断准确性。该系统可以帮助医生及早发现心肌梗死,从而加快治疗速度并改善患者预后。
Owing to the increased mortality of heart diseases worldwide, especially myocardial infarction (MI), early detection is essential for improved diagnosis and treatment. The main purpose of this study is to develop a myocardial infarction detection method that combines deep learning and image processing, focusing on abnormalities in left ventricular (LV) wall motion.
Methods
The proposed method primarily uses the LV wall motion movement as a feature to train an LSTM network for MI detection. LV wall motion annotated by expert cardiologists was used as the ground truth. Accuracy, sensitivity, specificity, and area under the curve (AUC) were used to evaluate model performance. The proposed method primarily uses LV wall motion as a feature, combined with LV size and image pixels, to improve diagnostic accuracy over existing computer-aided design (CAD) systems.
Results
The LSTM model achieved the highest diagnostic performance when trained on a combination of LV wall motion, LV size, and image pixel features with an accuracy of 95%, sensitivity of 96%, specificity of 94%, and an AUC value of 0.98. The LSTM model significantly outperformed models trained on individual feature sets or conventional machine learning algorithms. The inclusion of LV wall motion analysis improved accuracy by 10% compared to using only LV size and pixel data.
Conclusion
Our MI diagnosis system uses echocardiographic image analysis and LSTM-based deep learning to accurately detect LV wall motion issues related to MI. Compared with current CAD systems, the inclusion of LV wall motion analysis significantly improves diagnosis accuracy. The proposed system can help physicians detect MI early, thereby accelerating treatment and improving patient outcomes.
期刊介绍:
The purpose of Journal of Medical and Biological Engineering, JMBE, is committed to encouraging and providing the standard of biomedical engineering. The journal is devoted to publishing papers related to clinical engineering, biomedical signals, medical imaging, bio-informatics, tissue engineering, and so on. Other than the above articles, any contributions regarding hot issues and technological developments that help reach the purpose are also included.