{"title":"通过界面交联调节聚(乳酸)/羟基磷灰石复合材料的机械和热性能","authors":"Eylül Odabaş, Oğuz Öztürk, Esin Akarsu","doi":"10.1002/pc.28968","DOIUrl":null,"url":null,"abstract":"<jats:label/>Poly(lactic acid) (PLA) is a biodegradable and bioactive thermoplastic polymer. It has been widely used for hard tissue applications in orthopedic and dental fields. However, PLA is not able to form a direct bond with bone and this limits its applications. Therefore, PLA and hydroxyapatite (HAp) composites have gained significant attention to improve PLA performance. However, agglomeration of HAp in PLA matrix due to unfavored interfacial interactions between PLA and HAp directly affects the mechanical properties and stability of PLA/HAp composites. In this study, 3‐(glycidyloxypropyl)trimethoxysilane (GLYMO)‐modified HAp particles (G‐HAp) were synthesized and then incorporated into the PLA matrix to prepare PLA/G‐HAp composites. PLA/G‐HAp composites were prepared by mixing G‐HAp at 50 wt% with PLA (10 wt% in chloroform) solution. The resulting mixture was dried, ground, and molded into cylindrical shapes by pressure, and cured under N<jats:sub>2</jats:sub> atmosphere. The interface interactions of the obtained composites were elucidated by fourier transform infrared spectrometer (FTIR), scanning electron microscopy (SEM) and atomic force microscopy (AFM) analyses. It was observed that increased crosslinking density in the interface resulted in rougher surfaces. Thermal analyses demonstrated that T<jats:sub>g</jats:sub> of PLA shifted to higher temperatures in parallel with crosslinking density. Additionally, Vicker's hardness tests and compression tests were conducted to determine the effect of interfacial crosslinking, and improved hardness and Young's modulus were observed. In the final part of study, MTT assay was carried out to evaluate cytotoxicity of composites and PLA/G‐HAp displayed higher cytocompatibility compared to conventional PLA/HAp composite.Highlights<jats:list list-type=\"bullet\"> <jats:list-item>GLYMO modified HAp led to changes in the surface properties of composites.</jats:list-item> <jats:list-item>Increased crosslinking caused rougher surfaces for composites.</jats:list-item> <jats:list-item>T<jats:sub>g</jats:sub> shifted to higher temperatures in parallel with GLYMO mediated crosslinking.</jats:list-item> <jats:list-item>Composites containing GLYMO‐modified HAp particles exhibited significant improvement in mechanical properties.</jats:list-item> </jats:list>","PeriodicalId":20375,"journal":{"name":"Polymer Composites","volume":null,"pages":null},"PeriodicalIF":4.8000,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Modulation of mechanical and thermal properties of poly(lactic acid)/hydroxyapatite composites by interface crosslinking\",\"authors\":\"Eylül Odabaş, Oğuz Öztürk, Esin Akarsu\",\"doi\":\"10.1002/pc.28968\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<jats:label/>Poly(lactic acid) (PLA) is a biodegradable and bioactive thermoplastic polymer. It has been widely used for hard tissue applications in orthopedic and dental fields. However, PLA is not able to form a direct bond with bone and this limits its applications. Therefore, PLA and hydroxyapatite (HAp) composites have gained significant attention to improve PLA performance. However, agglomeration of HAp in PLA matrix due to unfavored interfacial interactions between PLA and HAp directly affects the mechanical properties and stability of PLA/HAp composites. In this study, 3‐(glycidyloxypropyl)trimethoxysilane (GLYMO)‐modified HAp particles (G‐HAp) were synthesized and then incorporated into the PLA matrix to prepare PLA/G‐HAp composites. PLA/G‐HAp composites were prepared by mixing G‐HAp at 50 wt% with PLA (10 wt% in chloroform) solution. The resulting mixture was dried, ground, and molded into cylindrical shapes by pressure, and cured under N<jats:sub>2</jats:sub> atmosphere. The interface interactions of the obtained composites were elucidated by fourier transform infrared spectrometer (FTIR), scanning electron microscopy (SEM) and atomic force microscopy (AFM) analyses. It was observed that increased crosslinking density in the interface resulted in rougher surfaces. Thermal analyses demonstrated that T<jats:sub>g</jats:sub> of PLA shifted to higher temperatures in parallel with crosslinking density. Additionally, Vicker's hardness tests and compression tests were conducted to determine the effect of interfacial crosslinking, and improved hardness and Young's modulus were observed. In the final part of study, MTT assay was carried out to evaluate cytotoxicity of composites and PLA/G‐HAp displayed higher cytocompatibility compared to conventional PLA/HAp composite.Highlights<jats:list list-type=\\\"bullet\\\"> <jats:list-item>GLYMO modified HAp led to changes in the surface properties of composites.</jats:list-item> <jats:list-item>Increased crosslinking caused rougher surfaces for composites.</jats:list-item> <jats:list-item>T<jats:sub>g</jats:sub> shifted to higher temperatures in parallel with GLYMO mediated crosslinking.</jats:list-item> <jats:list-item>Composites containing GLYMO‐modified HAp particles exhibited significant improvement in mechanical properties.</jats:list-item> </jats:list>\",\"PeriodicalId\":20375,\"journal\":{\"name\":\"Polymer Composites\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.8000,\"publicationDate\":\"2024-08-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polymer Composites\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1002/pc.28968\",\"RegionNum\":2,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, COMPOSITES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polymer Composites","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1002/pc.28968","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, COMPOSITES","Score":null,"Total":0}
Modulation of mechanical and thermal properties of poly(lactic acid)/hydroxyapatite composites by interface crosslinking
Poly(lactic acid) (PLA) is a biodegradable and bioactive thermoplastic polymer. It has been widely used for hard tissue applications in orthopedic and dental fields. However, PLA is not able to form a direct bond with bone and this limits its applications. Therefore, PLA and hydroxyapatite (HAp) composites have gained significant attention to improve PLA performance. However, agglomeration of HAp in PLA matrix due to unfavored interfacial interactions between PLA and HAp directly affects the mechanical properties and stability of PLA/HAp composites. In this study, 3‐(glycidyloxypropyl)trimethoxysilane (GLYMO)‐modified HAp particles (G‐HAp) were synthesized and then incorporated into the PLA matrix to prepare PLA/G‐HAp composites. PLA/G‐HAp composites were prepared by mixing G‐HAp at 50 wt% with PLA (10 wt% in chloroform) solution. The resulting mixture was dried, ground, and molded into cylindrical shapes by pressure, and cured under N2 atmosphere. The interface interactions of the obtained composites were elucidated by fourier transform infrared spectrometer (FTIR), scanning electron microscopy (SEM) and atomic force microscopy (AFM) analyses. It was observed that increased crosslinking density in the interface resulted in rougher surfaces. Thermal analyses demonstrated that Tg of PLA shifted to higher temperatures in parallel with crosslinking density. Additionally, Vicker's hardness tests and compression tests were conducted to determine the effect of interfacial crosslinking, and improved hardness and Young's modulus were observed. In the final part of study, MTT assay was carried out to evaluate cytotoxicity of composites and PLA/G‐HAp displayed higher cytocompatibility compared to conventional PLA/HAp composite.HighlightsGLYMO modified HAp led to changes in the surface properties of composites.Increased crosslinking caused rougher surfaces for composites.Tg shifted to higher temperatures in parallel with GLYMO mediated crosslinking.Composites containing GLYMO‐modified HAp particles exhibited significant improvement in mechanical properties.
期刊介绍:
Polymer Composites is the engineering and scientific journal serving the fields of reinforced plastics and polymer composites including research, production, processing, and applications. PC brings you the details of developments in this rapidly expanding area of technology long before they are commercial realities.