通过界面交联调节聚(乳酸)/羟基磷灰石复合材料的机械和热性能

IF 4.8 2区 材料科学 Q2 MATERIALS SCIENCE, COMPOSITES
Eylül Odabaş, Oğuz Öztürk, Esin Akarsu
{"title":"通过界面交联调节聚(乳酸)/羟基磷灰石复合材料的机械和热性能","authors":"Eylül Odabaş, Oğuz Öztürk, Esin Akarsu","doi":"10.1002/pc.28968","DOIUrl":null,"url":null,"abstract":"<jats:label/>Poly(lactic acid) (PLA) is a biodegradable and bioactive thermoplastic polymer. It has been widely used for hard tissue applications in orthopedic and dental fields. However, PLA is not able to form a direct bond with bone and this limits its applications. Therefore, PLA and hydroxyapatite (HAp) composites have gained significant attention to improve PLA performance. However, agglomeration of HAp in PLA matrix due to unfavored interfacial interactions between PLA and HAp directly affects the mechanical properties and stability of PLA/HAp composites. In this study, 3‐(glycidyloxypropyl)trimethoxysilane (GLYMO)‐modified HAp particles (G‐HAp) were synthesized and then incorporated into the PLA matrix to prepare PLA/G‐HAp composites. PLA/G‐HAp composites were prepared by mixing G‐HAp at 50 wt% with PLA (10 wt% in chloroform) solution. The resulting mixture was dried, ground, and molded into cylindrical shapes by pressure, and cured under N<jats:sub>2</jats:sub> atmosphere. The interface interactions of the obtained composites were elucidated by fourier transform infrared spectrometer (FTIR), scanning electron microscopy (SEM) and atomic force microscopy (AFM) analyses. It was observed that increased crosslinking density in the interface resulted in rougher surfaces. Thermal analyses demonstrated that T<jats:sub>g</jats:sub> of PLA shifted to higher temperatures in parallel with crosslinking density. Additionally, Vicker's hardness tests and compression tests were conducted to determine the effect of interfacial crosslinking, and improved hardness and Young's modulus were observed. In the final part of study, MTT assay was carried out to evaluate cytotoxicity of composites and PLA/G‐HAp displayed higher cytocompatibility compared to conventional PLA/HAp composite.Highlights<jats:list list-type=\"bullet\"> <jats:list-item>GLYMO modified HAp led to changes in the surface properties of composites.</jats:list-item> <jats:list-item>Increased crosslinking caused rougher surfaces for composites.</jats:list-item> <jats:list-item>T<jats:sub>g</jats:sub> shifted to higher temperatures in parallel with GLYMO mediated crosslinking.</jats:list-item> <jats:list-item>Composites containing GLYMO‐modified HAp particles exhibited significant improvement in mechanical properties.</jats:list-item> </jats:list>","PeriodicalId":20375,"journal":{"name":"Polymer Composites","volume":null,"pages":null},"PeriodicalIF":4.8000,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Modulation of mechanical and thermal properties of poly(lactic acid)/hydroxyapatite composites by interface crosslinking\",\"authors\":\"Eylül Odabaş, Oğuz Öztürk, Esin Akarsu\",\"doi\":\"10.1002/pc.28968\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<jats:label/>Poly(lactic acid) (PLA) is a biodegradable and bioactive thermoplastic polymer. It has been widely used for hard tissue applications in orthopedic and dental fields. However, PLA is not able to form a direct bond with bone and this limits its applications. Therefore, PLA and hydroxyapatite (HAp) composites have gained significant attention to improve PLA performance. However, agglomeration of HAp in PLA matrix due to unfavored interfacial interactions between PLA and HAp directly affects the mechanical properties and stability of PLA/HAp composites. In this study, 3‐(glycidyloxypropyl)trimethoxysilane (GLYMO)‐modified HAp particles (G‐HAp) were synthesized and then incorporated into the PLA matrix to prepare PLA/G‐HAp composites. PLA/G‐HAp composites were prepared by mixing G‐HAp at 50 wt% with PLA (10 wt% in chloroform) solution. The resulting mixture was dried, ground, and molded into cylindrical shapes by pressure, and cured under N<jats:sub>2</jats:sub> atmosphere. The interface interactions of the obtained composites were elucidated by fourier transform infrared spectrometer (FTIR), scanning electron microscopy (SEM) and atomic force microscopy (AFM) analyses. It was observed that increased crosslinking density in the interface resulted in rougher surfaces. Thermal analyses demonstrated that T<jats:sub>g</jats:sub> of PLA shifted to higher temperatures in parallel with crosslinking density. Additionally, Vicker's hardness tests and compression tests were conducted to determine the effect of interfacial crosslinking, and improved hardness and Young's modulus were observed. In the final part of study, MTT assay was carried out to evaluate cytotoxicity of composites and PLA/G‐HAp displayed higher cytocompatibility compared to conventional PLA/HAp composite.Highlights<jats:list list-type=\\\"bullet\\\"> <jats:list-item>GLYMO modified HAp led to changes in the surface properties of composites.</jats:list-item> <jats:list-item>Increased crosslinking caused rougher surfaces for composites.</jats:list-item> <jats:list-item>T<jats:sub>g</jats:sub> shifted to higher temperatures in parallel with GLYMO mediated crosslinking.</jats:list-item> <jats:list-item>Composites containing GLYMO‐modified HAp particles exhibited significant improvement in mechanical properties.</jats:list-item> </jats:list>\",\"PeriodicalId\":20375,\"journal\":{\"name\":\"Polymer Composites\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.8000,\"publicationDate\":\"2024-08-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polymer Composites\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1002/pc.28968\",\"RegionNum\":2,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, COMPOSITES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polymer Composites","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1002/pc.28968","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, COMPOSITES","Score":null,"Total":0}
引用次数: 0

摘要

聚乳酸(PLA)是一种可生物降解且具有生物活性的热塑性聚合物。它已被广泛应用于整形外科和牙科领域的硬组织应用。然而,聚乳酸不能与骨骼直接结合,这限制了它的应用。因此,聚乳酸和羟基磷灰石(HAp)复合材料在提高聚乳酸性能方面受到了广泛关注。然而,由于聚乳酸和 HAp 之间不利的界面相互作用,HAp 在聚乳酸基质中的团聚直接影响了聚乳酸/HAp 复合材料的机械性能和稳定性。本研究合成了 3-(缩水甘油氧基丙基)三甲氧基硅烷(GLYMO)改性的 HAp 颗粒(G-HAp),然后将其加入聚乳酸基体中制备聚乳酸/G-HAp 复合材料。将 50 wt% 的 G-HAp 与聚乳酸(10 wt%,氯仿)溶液混合,制备聚乳酸/G-HAp 复合材料。所得混合物经干燥、研磨、加压成型为圆柱形,并在 N2 大气中固化。通过傅立叶变换红外光谱仪(FTIR)、扫描电子显微镜(SEM)和原子力显微镜(AFM)分析,阐明了所得复合材料的界面相互作用。结果表明,界面交联密度的增加导致表面更加粗糙。热分析表明,聚乳酸的 Tg 随交联密度的增加而升高。此外,还进行了维氏硬度测试和压缩测试,以确定界面交联的影响,结果表明硬度和杨氏模量均有所提高。在研究的最后部分,进行了 MTT 试验以评估复合材料的细胞毒性,与传统的 PLA/HAp 复合材料相比,PLA/G-HAp 显示出更高的细胞相容性。交联度的增加使复合材料的表面更粗糙。在 GLYMO 介导交联的同时,Tg 转移到更高的温度。含有 GLYMO 改性 HAp 颗粒的复合材料的机械性能显著提高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Modulation of mechanical and thermal properties of poly(lactic acid)/hydroxyapatite composites by interface crosslinking

Modulation of mechanical and thermal properties of poly(lactic acid)/hydroxyapatite composites by interface crosslinking
Poly(lactic acid) (PLA) is a biodegradable and bioactive thermoplastic polymer. It has been widely used for hard tissue applications in orthopedic and dental fields. However, PLA is not able to form a direct bond with bone and this limits its applications. Therefore, PLA and hydroxyapatite (HAp) composites have gained significant attention to improve PLA performance. However, agglomeration of HAp in PLA matrix due to unfavored interfacial interactions between PLA and HAp directly affects the mechanical properties and stability of PLA/HAp composites. In this study, 3‐(glycidyloxypropyl)trimethoxysilane (GLYMO)‐modified HAp particles (G‐HAp) were synthesized and then incorporated into the PLA matrix to prepare PLA/G‐HAp composites. PLA/G‐HAp composites were prepared by mixing G‐HAp at 50 wt% with PLA (10 wt% in chloroform) solution. The resulting mixture was dried, ground, and molded into cylindrical shapes by pressure, and cured under N2 atmosphere. The interface interactions of the obtained composites were elucidated by fourier transform infrared spectrometer (FTIR), scanning electron microscopy (SEM) and atomic force microscopy (AFM) analyses. It was observed that increased crosslinking density in the interface resulted in rougher surfaces. Thermal analyses demonstrated that Tg of PLA shifted to higher temperatures in parallel with crosslinking density. Additionally, Vicker's hardness tests and compression tests were conducted to determine the effect of interfacial crosslinking, and improved hardness and Young's modulus were observed. In the final part of study, MTT assay was carried out to evaluate cytotoxicity of composites and PLA/G‐HAp displayed higher cytocompatibility compared to conventional PLA/HAp composite.Highlights GLYMO modified HAp led to changes in the surface properties of composites. Increased crosslinking caused rougher surfaces for composites. Tg shifted to higher temperatures in parallel with GLYMO mediated crosslinking. Composites containing GLYMO‐modified HAp particles exhibited significant improvement in mechanical properties.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Polymer Composites
Polymer Composites 工程技术-材料科学:复合
CiteScore
7.50
自引率
32.70%
发文量
673
审稿时长
3.1 months
期刊介绍: Polymer Composites is the engineering and scientific journal serving the fields of reinforced plastics and polymer composites including research, production, processing, and applications. PC brings you the details of developments in this rapidly expanding area of technology long before they are commercial realities.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信