{"title":"过渡金属催化 C-H 键官能化 C-糖苷的新进展","authors":"Zanjila Azeem, Sunny Maurya, Mohammad Ovais, Rekha Sagwan, Atul Dubey, Pintu Kumar Mandal","doi":"10.2174/0113852728326485240815110646","DOIUrl":null,"url":null,"abstract":": This review summarizes the recent trends in the transition-metal-catalyzed C-H bond functionalization approach to access C-branched (hetero)aryl/alkenyl/alkyl glycosides with reaction characteristics and proposed mechanisms. Recently, the Transition-metal-catalyzed C-H functionalization has arisen as a groundbreaking and versatile method for producing potent C-branched glycosides feasibly and efficiently. Nowadays, site-selective functionalization of C-H bonds in carbohydrate chemistry is highly demanded, owing to the intricate and highly stable nature of C-H bonds. In this context, we systematically summarize the C-H glycosylation of arenes, C-H arylation of glycoside, and Cattelani-strategy with mechanistic investigation. Also, the applications of transition-metal-catalyzed C-glycosylation for the formation of biologically active molecules are discussed.","PeriodicalId":10926,"journal":{"name":"Current Organic Chemistry","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Emerging Advances in Transition Metal-Catalyzed C-H Bond Functionalizations Towards C-Glycosides\",\"authors\":\"Zanjila Azeem, Sunny Maurya, Mohammad Ovais, Rekha Sagwan, Atul Dubey, Pintu Kumar Mandal\",\"doi\":\"10.2174/0113852728326485240815110646\",\"DOIUrl\":null,\"url\":null,\"abstract\":\": This review summarizes the recent trends in the transition-metal-catalyzed C-H bond functionalization approach to access C-branched (hetero)aryl/alkenyl/alkyl glycosides with reaction characteristics and proposed mechanisms. Recently, the Transition-metal-catalyzed C-H functionalization has arisen as a groundbreaking and versatile method for producing potent C-branched glycosides feasibly and efficiently. Nowadays, site-selective functionalization of C-H bonds in carbohydrate chemistry is highly demanded, owing to the intricate and highly stable nature of C-H bonds. In this context, we systematically summarize the C-H glycosylation of arenes, C-H arylation of glycoside, and Cattelani-strategy with mechanistic investigation. Also, the applications of transition-metal-catalyzed C-glycosylation for the formation of biologically active molecules are discussed.\",\"PeriodicalId\":10926,\"journal\":{\"name\":\"Current Organic Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2024-09-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Organic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.2174/0113852728326485240815110646\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.2174/0113852728326485240815110646","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Emerging Advances in Transition Metal-Catalyzed C-H Bond Functionalizations Towards C-Glycosides
: This review summarizes the recent trends in the transition-metal-catalyzed C-H bond functionalization approach to access C-branched (hetero)aryl/alkenyl/alkyl glycosides with reaction characteristics and proposed mechanisms. Recently, the Transition-metal-catalyzed C-H functionalization has arisen as a groundbreaking and versatile method for producing potent C-branched glycosides feasibly and efficiently. Nowadays, site-selective functionalization of C-H bonds in carbohydrate chemistry is highly demanded, owing to the intricate and highly stable nature of C-H bonds. In this context, we systematically summarize the C-H glycosylation of arenes, C-H arylation of glycoside, and Cattelani-strategy with mechanistic investigation. Also, the applications of transition-metal-catalyzed C-glycosylation for the formation of biologically active molecules are discussed.
期刊介绍:
Current Organic Chemistry aims to provide in-depth/mini reviews on the current progress in various fields related to organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic and green chemistry, suitable aspects of medicinal chemistry and polymer chemistry, as well as analytical methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by chosen experts who are internationally known for their eminent research contributions. The Journal also accepts high quality research papers focusing on hot topics, highlights and letters besides thematic issues in these fields. Current Organic Chemistry should prove to be of great interest to organic chemists in academia and industry, who wish to keep abreast with recent developments in key fields of organic chemistry.