不同激素受体乳腺癌亚型中乳腺癌风险因素的因果效应:双样本孟德尔随机研究

Renée MG Verdiesen, Mehrnoosh Shokouhi, Stephen Burgess, Sander Canisius, Jenny Chang-Claude, Stig E Bojesen, Marjanka K Schmidt
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引用次数: 0

摘要

背景 目前尚不清楚既定的乳腺癌风险因素是否对不同激素受体乳腺癌亚型产生类似的因果效应。我们估计并比较了身高、体重指数 (BMI)、2 型糖尿病、初潮年龄、绝经年龄、乳房密度、饮酒量、经常吸烟和体育锻炼在这些亚型中的因果关系估计值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Causal effects of breast cancer risk factors across hormone receptor breast cancer subtypes: A two-sample Mendelian randomization study
Background It is unclear if established breast cancer risk factors exert similar causal effects across hormone receptor breast cancer subtypes. We estimated and compared causal estimates of height, body mass index (BMI), type 2 diabetes, age at menarche, age at menopause, breast density, alcohol consumption, regular smoking, and physical activity across these subtypes.
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