{"title":"生物阻抗是烟草诱发口腔病变的诊断工具：一项混合模型横断面研究","authors":"Vaibhav Gupta, Poonam Goel, Usha Agrawal, Neena Chaudhary, Garima Jain, Deepak Gupta","doi":"arxiv-2408.11886","DOIUrl":null,"url":null,"abstract":"Introduction: Electrical impedance spectroscopy (EIS) has recently developed\nas a novel diagnostic device for screening and evaluating cervical dysplasia,\nprostate cancer, breast cancer and basal cell carcinoma. The current study\naimed to validate and evaluate bioimpedance as a diagnostic tool for\ntobacco-induced oral lesions. Methodology: The study comprised 50 OSCC and OPMD\ntissue specimens for in-vitro study and 320 subjects for in vivo study.\nBioimpedance device prepared and calibrated. EIS measurements were done for the\nhabit and control groups and were compared. Results: The impedance value in the\ncontrol group was significantly higher compared to the OPMD and OSCC groups.\nDiagnosis based on BIS measurements has a sensitivity of 95.9% and a\nspecificity of 86.7%. Conclusion: Bioimpedance device can help in\ndecision-making for differentiating OPMD and OSCC cases and their management,\nespecially in primary healthcare settings. Keywords: Impedance, Cancer, Diagnosis, Device, Community","PeriodicalId":501266,"journal":{"name":"arXiv - QuanBio - Quantitative Methods","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bioimpedance a Diagnostic Tool for Tobacco Induced Oral Lesions: a Mixed Model cross-sectional study\",\"authors\":\"Vaibhav Gupta, Poonam Goel, Usha Agrawal, Neena Chaudhary, Garima Jain, Deepak Gupta\",\"doi\":\"arxiv-2408.11886\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Electrical impedance spectroscopy (EIS) has recently developed\\nas a novel diagnostic device for screening and evaluating cervical dysplasia,\\nprostate cancer, breast cancer and basal cell carcinoma. The current study\\naimed to validate and evaluate bioimpedance as a diagnostic tool for\\ntobacco-induced oral lesions. Methodology: The study comprised 50 OSCC and OPMD\\ntissue specimens for in-vitro study and 320 subjects for in vivo study.\\nBioimpedance device prepared and calibrated. EIS measurements were done for the\\nhabit and control groups and were compared. Results: The impedance value in the\\ncontrol group was significantly higher compared to the OPMD and OSCC groups.\\nDiagnosis based on BIS measurements has a sensitivity of 95.9% and a\\nspecificity of 86.7%. Conclusion: Bioimpedance device can help in\\ndecision-making for differentiating OPMD and OSCC cases and their management,\\nespecially in primary healthcare settings. Keywords: Impedance, Cancer, Diagnosis, Device, Community\",\"PeriodicalId\":501266,\"journal\":{\"name\":\"arXiv - QuanBio - Quantitative Methods\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-08-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"arXiv - QuanBio - Quantitative Methods\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/arxiv-2408.11886\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"arXiv - QuanBio - Quantitative Methods","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/arxiv-2408.11886","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
导言：电阻抗光谱（EIS）是最近发展起来的一种新型诊断设备，可用于筛查和评估宫颈发育不良、前列腺癌、乳腺癌和基底细胞癌。本研究旨在验证和评估生物阻抗作为烟草引起的口腔病变的诊断工具。研究方法：生物阻抗装置的准备和校准。准备并校准了生物阻抗装置，对习惯组和对照组进行了 EIS 测量并进行了比较。结果：基于 BIS 测量的诊断灵敏度为 95.9%，特异度为 86.7%。结论生物阻抗仪有助于对OPMD和OSCC病例进行鉴别和管理，尤其是在基层医疗机构。关键词阻抗 癌症 诊断 设备 社区
Bioimpedance a Diagnostic Tool for Tobacco Induced Oral Lesions: a Mixed Model cross-sectional study
Introduction: Electrical impedance spectroscopy (EIS) has recently developed
as a novel diagnostic device for screening and evaluating cervical dysplasia,
prostate cancer, breast cancer and basal cell carcinoma. The current study
aimed to validate and evaluate bioimpedance as a diagnostic tool for
tobacco-induced oral lesions. Methodology: The study comprised 50 OSCC and OPMD
tissue specimens for in-vitro study and 320 subjects for in vivo study.
Bioimpedance device prepared and calibrated. EIS measurements were done for the
habit and control groups and were compared. Results: The impedance value in the
control group was significantly higher compared to the OPMD and OSCC groups.
Diagnosis based on BIS measurements has a sensitivity of 95.9% and a
specificity of 86.7%. Conclusion: Bioimpedance device can help in
decision-making for differentiating OPMD and OSCC cases and their management,
especially in primary healthcare settings. Keywords: Impedance, Cancer, Diagnosis, Device, Community
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