N-Heterocyclic Carbene (NHC) 催化的丙烯酰胺尾对尾二聚化反应

Synthesis Pub Date : 2024-08-14 DOI:10.1055/s-0043-1775037
Chensheng Zhao, Bingwei Zhou
{"title":"N-Heterocyclic Carbene (NHC) 催化的丙烯酰胺尾对尾二聚化反应","authors":"Chensheng Zhao, Bingwei Zhou","doi":"10.1055/s-0043-1775037","DOIUrl":null,"url":null,"abstract":"<p>The tail-to-tail dimerization of acrylamides enables the formation of diamides. However, only one example of <i>N</i>,<i>N</i>-dimethylacrylamide has been described in the literature. Herein, an NHC-catalyzed tail-to-tail dimerization of acrylamides in moderate to excellent yields is presented. In this context, <i>N</i>-arylacrylamides are susceptible to the dimerization reaction, which features high reaction efficiency, good <i>E</i>-selectivity, and easy operation.</p> ","PeriodicalId":501298,"journal":{"name":"Synthesis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"N-Heterocyclic Carbene (NHC)-Catalyzed Tail-to-Tail Dimerization of Acrylamides\",\"authors\":\"Chensheng Zhao, Bingwei Zhou\",\"doi\":\"10.1055/s-0043-1775037\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The tail-to-tail dimerization of acrylamides enables the formation of diamides. However, only one example of <i>N</i>,<i>N</i>-dimethylacrylamide has been described in the literature. Herein, an NHC-catalyzed tail-to-tail dimerization of acrylamides in moderate to excellent yields is presented. In this context, <i>N</i>-arylacrylamides are susceptible to the dimerization reaction, which features high reaction efficiency, good <i>E</i>-selectivity, and easy operation.</p> \",\"PeriodicalId\":501298,\"journal\":{\"name\":\"Synthesis\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-08-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Synthesis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0043-1775037\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synthesis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0043-1775037","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

丙烯酰胺的尾对尾二聚化可以形成二酰胺。然而,文献中只有一个 N,N-二甲基丙烯酰胺的实例。本文介绍了一种 NHC 催化的丙烯酰胺尾对尾二聚反应,收率中等至极佳。在这种情况下,N-芳基丙烯酰胺容易发生二聚反应,该反应具有反应效率高、E-选择性好和操作简便等特点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

N-Heterocyclic Carbene (NHC)-Catalyzed Tail-to-Tail Dimerization of Acrylamides

N-Heterocyclic Carbene (NHC)-Catalyzed Tail-to-Tail Dimerization of Acrylamides

The tail-to-tail dimerization of acrylamides enables the formation of diamides. However, only one example of N,N-dimethylacrylamide has been described in the literature. Herein, an NHC-catalyzed tail-to-tail dimerization of acrylamides in moderate to excellent yields is presented. In this context, N-arylacrylamides are susceptible to the dimerization reaction, which features high reaction efficiency, good E-selectivity, and easy operation.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信