留下还是离开?离家接受手术的患者下肢关节置换术的结果:比较患者居住地和医院偏远程度的 AOANJRR 横截面分析

Corey Scholes, Carl Holder, Christopher Vertullo, Matthew Lawrence Broadhead
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All-cause revision within the two-year period after surgery for primary total knee arthroplasty (TKA) and primary total hip arthroplasty (THA) for osteoarthritis as the primary diagnosis was selected as the primary outcome. A directed-acyclic graph approach was used to prioritise covariates for inclusion in a Cox proportional hazards regression model. Cumulative percent revision (CPR) rates with 95% confidence intervals was reported with hazard ratios between subgroups of residential and hospital remoteness. Results: The two-year CPR for primary TKA ranged from 1.8% (95% CI 1.7 - 1.9) to 2.2% (95% CI 1.8 - 2.7). Patients residing in rural-remote areas who travelled to a metro-regional hospital displayed a significantly higher rate of revision following TKA compared to patients that were treated at a rural-remote hospital (HR: 1.11, 95% CI 1.05 - 1.18, P = 0.001) within two-year follow-up of the primary procedure. 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引用次数: 0

摘要

目的:患者居住地的偏远程度与手术后结果(如早期植入物翻修)之间的关系还有待研究。本研究旨在评估初次髋关节或膝关节全关节置换术后 2 年内全因翻修的发生率是否会随初次手术时居住地的偏远程度而变化。研究方法对澳大利亚骨科协会全国关节置换登记处(AOANJRR)1999年9月1日至2022年12月31日的数据进行了分析。采用莫纳什偏远地区分类修正模型(2015)将患者居住地和医院所在地分为大都市地区(MM 1-2)和农村偏远地区(MM 3-7)。选择以骨关节炎为主要诊断的初级全膝关节置换术(TKA)和初级全髋关节置换术(THA)术后两年内的全因翻修作为主要结果。采用有向圆环图法确定协变量的优先次序,并将其纳入 Cox 比例危险度回归模型。报告了累计翻修率(CPR)和95%置信区间,以及居住地和医院偏远程度亚组之间的危险比。结果:初次 TKA 两年的 CPR 从 1.8%(95% CI 1.7 - 1.9)到 2.2%(95% CI 1.8 - 2.7)不等。与在偏远农村地区医院接受治疗的患者相比,居住在偏远农村地区并前往大都市地区医院接受治疗的患者在初次手术后两年随访期内的 TKA 术后翻修率明显更高(HR:1.11,95% CI 1.05 - 1.18,P = 0.001)。居住在偏远农村地区并在这些地区接受手术的患者,其关节置换术后复发率明显低于在大都市地区接受手术的患者(HR=0.90,95%CI 0.85 - 0.95,P =0.001)。在随访期间,感染是患者进行TKA翻修的主要原因。初次全髋关节置换术的患者和医院组合在翻修风险方面没有明显差异。结论旅行距离(而非患者居住地的偏远程度)可能与初次全髋关节置换术早期翻修(2年内)的累积风险有关,特别是对于旅行到外地的地区/偏远地区患者,但对于接受全髋关节置换术的患者则无关。需要进一步研究翻修手术前的服务利用率,以明确偏远地区和旅行距离之间的翻修差异是由于地区和大都市外科医生提供翻修关节成形术的临床阈值存在差异,还是由于初次手术的结果有所改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Stay or go? Outcomes of lower limb arthroplasty in patients travelling away from home for surgery: A cross-sectional analysis of the AOANJRR comparing patient residence and hospital remoteness
Purpose: The relationship between remoteness of patient residence and post-surgical outcomes, such as early implant revision, has yet to be examined. The aim of this study was to assess whether the incidence of all-cause revision at up to 2 years following primary hip or knee total joint arthroplasty varies with the remoteness of a person's place of residence at the time of the primary procedure. Methods: An analysis was performed of data from the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) from 1 Sept 1999 to 31 Dec 2022. The Modified Monash Model (2015) of remoteness classification was used to categorise patient residence and hospital location into metro-regional (MM 1-2) and rural-remote (MM 3-7). All-cause revision within the two-year period after surgery for primary total knee arthroplasty (TKA) and primary total hip arthroplasty (THA) for osteoarthritis as the primary diagnosis was selected as the primary outcome. A directed-acyclic graph approach was used to prioritise covariates for inclusion in a Cox proportional hazards regression model. Cumulative percent revision (CPR) rates with 95% confidence intervals was reported with hazard ratios between subgroups of residential and hospital remoteness. Results: The two-year CPR for primary TKA ranged from 1.8% (95% CI 1.7 - 1.9) to 2.2% (95% CI 1.8 - 2.7). Patients residing in rural-remote areas who travelled to a metro-regional hospital displayed a significantly higher rate of revision following TKA compared to patients that were treated at a rural-remote hospital (HR: 1.11, 95% CI 1.05 - 1.18, P = 0.001) within two-year follow-up of the primary procedure. Patients residing in rural-remote areas that stayed in these areas for their operation displayed a significantly reduced revision rate compared to metro-regional patients that stayed in-area for their joint replacement (HR=0.90, 95%CI 0.85 - 0.95, P <0.001). Infection was the dominant reason for TKA revision for patients in the follow-up period. No discernible differences in revision risk were observed between patient and hospital combinations for primary total hip replacement. Conclusions: Travel distance, but not remoteness of a patient's place of residence may be associated with cumulative risk of early revision (within 2 years) of primary TKA, particularly in regional/remote patients travelling out of area, but not for patients undergoing THA. Further work linking service utilisation prior to a revision procedure is required to clarify whether differences in revision between remoteness and travel distances are due to variability in the clinical threshold for offering revision arthroplasty between regional and metropolitan surgeons or improved outcomes of the primary procedure.
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