接受体位性正位性心动过速综合征(POTS)调查的人的症状严重程度随时间变化的相关性和预测因素。

IF 2.9 3区 医学 Q2 PSYCHIATRY
Iris Knoop,Annie S K Jones,Nicholas Gall,Sam Norton,William Pascoe,Rona Moss-Morris
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引用次数: 0

摘要

目的体位性正位性心动过速综合征(POTS)是一种鲜为人知的慢性疾病,其特点是站立时心跳会莫名其妙地过度加快。本研究旨在调查出现 POTS 类似症状的患者的心理社会学和生理学相关因素以及随着时间推移症状严重程度的预测因素。患者在就诊前一个月和就诊 6 个月后填写调查问卷。诊断、血压(BP)和心率(HR)数据均来自医疗记录。结果随着时间的推移,骨转移和小纤维神经病(SFN)症状保持稳定,并与痛苦、心脏焦虑、对疾病的威胁性看法以及对症状的认知行为反应显著相关,但与情绪反应或社会支持无关。基线心理社会因素共同解释了48%(F = 5.37,p < .001)的正压症状变异,解释了35%(F = 3.49,p < .001)的SFN基线症状变异,但在控制基线症状的情况下,6个月时的症状变异并不显著。血液动力学指标对 6 个月时的正压症状方差的解释率为 4% (F = 3.37, p = .026)。心理社会因素解释了基线症状的大量差异。由于症状并未随时间推移而改变或改善,基线症状占 6 个月时症状差异的大部分。在进行医学治疗的同时,采取综合方法解决社会心理因素,可能会促进该群体对病情的适应,减轻症状负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlates and predictors of symptom severity over time in people under investigation for postural orthostatic tachycardia syndrome (POTS).
OBJECTIVE Postural Orthostatic Tachycardia Syndrome (POTS) is a poorly understood chronic disorder characterised by an unexplained excessive increase in heartbeat upon standing. The aim of this study was to investigate psychosocial and physiological correlates and predictors of symptom severity over time in patients presenting with POTS-like symptoms. METHODS Longitudinal cohort study of patients under investigation for POTS (n = 149). Patients completed questionnaires at one month pre-clinic appointment and 6 months later. Diagnosis, blood pressure (BP) and heart rate (HR) measures were collected from medical records. Data were analysed using hierarchical linear multiple regression. RESULTS Orthostatic and small fibre neuropathy (SFN) symptoms remained stable over time and were significantly correlated with distress, cardiac anxiety, threatening views of the illness, and cognitive-behavioural responses to symptoms, but not with emotional reactivity or social support. Baseline psychosocial factors collectively explained 48% (F = 5.37, p < .001) of the variance in orthostatic symptoms, and 35% (F = 3.49, p < .001) of the variance of SFN symptoms at baseline, but a non-significant amount of variance in symptoms at 6 months when controlling for baseline symptoms. Haemodynamic measures explained a significant 4% (F = 3.37, p = .026) of variance of orthostatic symptoms at 6 months. CONCLUSION Symptom burden in patients with suspected POTS remained high over 6 months. Psychosocial factors explained a large amount of the variance in symptoms at baseline. As symptoms did not change/improve over time, baseline symptoms accounted for most of the variance in symptoms at 6 months. An integrated approach addressing psychosocial factors alongside medical treatments may promote adjustment to the condition and lessen symptom burden for this group.
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来源期刊
Psychosomatic Medicine
Psychosomatic Medicine 医学-精神病学
CiteScore
5.10
自引率
0.00%
发文量
258
审稿时长
4-8 weeks
期刊介绍: Psychosomatic Medicine is the official peer-reviewed journal of the American Psychosomatic Society. The journal publishes experimental, clinical, and epidemiological studies on the role of psychological and social factors in the biological and behavioral processes relevant to health and disease. Psychosomatic Medicine is an interdisciplinary peer-reviewed journal devoted to high-quality science on biobehavioral mechanisms, brain-behavior interactions relevant to physical and mental disorders, as well as interventions in clinical and public health settings. Psychosomatic Medicine was founded in 1939 and publishes interdisciplinary research articles relevant to medicine, psychiatry, psychology, and other health-related disciplines. The print journal is published nine times a year; most articles are published online ahead of print. Supplementary issues may contain reports of conferences at which original research was presented in areas relevant to the psychosomatic and behavioral medicine.
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