Emanuel F. Teixeira, Carine P. Beatrici, Heitor C. M. Fernandes, Leonardo G. Brunnet
{"title":"二元混合物中的分离与活性环之间的差异收缩","authors":"Emanuel F. Teixeira, Carine P. Beatrici, Heitor C. M. Fernandes, Leonardo G. Brunnet","doi":"arxiv-2409.02814","DOIUrl":null,"url":null,"abstract":"Cell cortex contraction is essential for shaping cells, enabling movement,\nensuring proper division, maintaining tissue integrity, guiding development,\nand responding to mechanical signals - all critical for the life and health of\nmulticellular organisms. Differential contractions in cell membranes,\nparticularly when cells of different types interact, play a crucial role in the\nemergence of segregation. In this study, we introduce a model where rings\ncomposed of active particles interact through differential membrane contraction\nwithin a specified cutoff distance. We demonstrate that segregation arises\nsolely from differential contraction, with the activity of the rings\nfunctioning similarly to an effective temperature. Additionally, we observed\nthat segregation involves cluster fusion-diffusion process. However, the decay\nexponent of the segregation parameter we found is close to $\\lambda \\sim -1/3$,\nwhich differs from the $\\lambda \\sim -1/4$ predicted by previous theoretical\napproaches and simulations.","PeriodicalId":501369,"journal":{"name":"arXiv - PHYS - Computational Physics","volume":"85 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Segregation in binary mixture with differential contraction among active rings\",\"authors\":\"Emanuel F. Teixeira, Carine P. Beatrici, Heitor C. M. Fernandes, Leonardo G. Brunnet\",\"doi\":\"arxiv-2409.02814\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cell cortex contraction is essential for shaping cells, enabling movement,\\nensuring proper division, maintaining tissue integrity, guiding development,\\nand responding to mechanical signals - all critical for the life and health of\\nmulticellular organisms. Differential contractions in cell membranes,\\nparticularly when cells of different types interact, play a crucial role in the\\nemergence of segregation. In this study, we introduce a model where rings\\ncomposed of active particles interact through differential membrane contraction\\nwithin a specified cutoff distance. We demonstrate that segregation arises\\nsolely from differential contraction, with the activity of the rings\\nfunctioning similarly to an effective temperature. Additionally, we observed\\nthat segregation involves cluster fusion-diffusion process. However, the decay\\nexponent of the segregation parameter we found is close to $\\\\lambda \\\\sim -1/3$,\\nwhich differs from the $\\\\lambda \\\\sim -1/4$ predicted by previous theoretical\\napproaches and simulations.\",\"PeriodicalId\":501369,\"journal\":{\"name\":\"arXiv - PHYS - Computational Physics\",\"volume\":\"85 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"arXiv - PHYS - Computational Physics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/arxiv-2409.02814\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"arXiv - PHYS - Computational Physics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/arxiv-2409.02814","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Segregation in binary mixture with differential contraction among active rings
Cell cortex contraction is essential for shaping cells, enabling movement,
ensuring proper division, maintaining tissue integrity, guiding development,
and responding to mechanical signals - all critical for the life and health of
multicellular organisms. Differential contractions in cell membranes,
particularly when cells of different types interact, play a crucial role in the
emergence of segregation. In this study, we introduce a model where rings
composed of active particles interact through differential membrane contraction
within a specified cutoff distance. We demonstrate that segregation arises
solely from differential contraction, with the activity of the rings
functioning similarly to an effective temperature. Additionally, we observed
that segregation involves cluster fusion-diffusion process. However, the decay
exponent of the segregation parameter we found is close to $\lambda \sim -1/3$,
which differs from the $\lambda \sim -1/4$ predicted by previous theoretical
approaches and simulations.