用于骨修复的钙基纳米线

Yuqi Sun, Yuanbo Wang
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引用次数: 0

摘要

老年人群、严重创伤、先天畸形、骨肿瘤切除、感染等导致的骨缺损是骨科临床治疗中面临的严重问题,对人体健康和生命造成极大危害,一般需要通过外力干预来促进骨愈合。考虑到钙离子的成骨促进作用,本研究合成了 Ca-POM 纳米线,通过释放钙离子促进成骨过程。细胞毒性测试表明,该材料具有良好的生物相容性。此外,茜素红 S 染色结果表明,该材料可促进骨生成,表明其有潜力成为骨修复的理想候选材料。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Calcium-based nanowires for bone repair
Bone defects due to the older population, severe trauma, congenital malformations, resection of bone tumors, and infections are serious problems faced in orthopedic clinical treatment, posing great hazards to human health and life, and external interventions are generally required to promote bone healing. Considering the osteogenic promotion of calcium ions, Ca-POM nanowires were synthesized in this study to facilitate the osteogenesis process through the release of calcium ions. The cytotoxicity test showed that the material possesses good biocompatibility. Furthermore, the Alizarin Red S staining demonstrated that the material could promote osteogenesis, indicating its potential as an ideal candidate for bone repair.
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