镁基植入物:改善生物力学和生物腐蚀性能的合金和涂层策略

IF 2.5 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY
Triloki Nath Mishra, Amaresh Kumar, Shashi Bhushan Prasad
{"title":"镁基植入物:改善生物力学和生物腐蚀性能的合金和涂层策略","authors":"Triloki Nath Mishra, Amaresh Kumar, Shashi Bhushan Prasad","doi":"10.1177/14644207241269609","DOIUrl":null,"url":null,"abstract":"Magnesium (Mg) based materials show great promise as temporary implant applications owing to their biocompatibility and biodegradability. These characteristics remove the risk of subsequent surgery to extract the implant once the process of bone tissue healing is finished. Additionally, its density and elastic modulus are near to those of natural bone, thereby reducing the stress-shielding effect. Mg is mostly recognized for its osteoconductive abilities, which implies that it encourages the generation of fresh bone tissue. It also has antimicrobial properties, which lower the possibility of infections leading to implant failure. Moreover, the rapid bio-corrosion of pure Mg in the presence of physiological fluids is a serious concern. The implant's mechanical integrity deteriorates as a result of this corrosion before the surrounding tissue has completely recovered. To address these issues, this review focused on approaches, including alloying, the creation of composites, and surface coating, which can increase their biomechanical and bio-corrosion properties. In vitro analysis of biomechanical and bio-corrosion characteristics of newly manufactured Mg-based implant material is presented in this article. In addition to this application, a list of approved devices made from Mg-based material is highlighted. Furthermore, the present challenges and prospects for future research are also discussed.","PeriodicalId":20630,"journal":{"name":"Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications","volume":"68 1","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Magnesium based implants: Alloying and coating strategies for improvement in its biomechanical and biocorrosion properties\",\"authors\":\"Triloki Nath Mishra, Amaresh Kumar, Shashi Bhushan Prasad\",\"doi\":\"10.1177/14644207241269609\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Magnesium (Mg) based materials show great promise as temporary implant applications owing to their biocompatibility and biodegradability. These characteristics remove the risk of subsequent surgery to extract the implant once the process of bone tissue healing is finished. Additionally, its density and elastic modulus are near to those of natural bone, thereby reducing the stress-shielding effect. Mg is mostly recognized for its osteoconductive abilities, which implies that it encourages the generation of fresh bone tissue. It also has antimicrobial properties, which lower the possibility of infections leading to implant failure. Moreover, the rapid bio-corrosion of pure Mg in the presence of physiological fluids is a serious concern. The implant's mechanical integrity deteriorates as a result of this corrosion before the surrounding tissue has completely recovered. To address these issues, this review focused on approaches, including alloying, the creation of composites, and surface coating, which can increase their biomechanical and bio-corrosion properties. In vitro analysis of biomechanical and bio-corrosion characteristics of newly manufactured Mg-based implant material is presented in this article. In addition to this application, a list of approved devices made from Mg-based material is highlighted. Furthermore, the present challenges and prospects for future research are also discussed.\",\"PeriodicalId\":20630,\"journal\":{\"name\":\"Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications\",\"volume\":\"68 1\",\"pages\":\"\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-08-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1177/14644207241269609\",\"RegionNum\":4,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1177/14644207241269609","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

摘要

镁(Mg)基材料因其生物相容性和生物可降解性,在临时植入应用中大有可为。这些特性消除了骨组织愈合过程结束后再进行手术取出植入物的风险。此外,镁的密度和弹性模量与天然骨接近,从而降低了应力屏蔽效应。镁被公认为具有骨诱导能力,这意味着它能促进新鲜骨组织的生成。它还具有抗菌特性,可降低感染导致植入失败的可能性。此外,纯镁在生理液体中的快速生物腐蚀也是一个令人担忧的问题。在周围组织完全恢复之前,这种腐蚀会导致植入物的机械完整性恶化。为了解决这些问题,本综述重点讨论了可以提高生物力学和生物腐蚀性能的方法,包括合金化、复合材料的制造和表面涂层。本文对新制造的镁基植入材料的生物力学和生物腐蚀特性进行了体外分析。除此应用外,文章还重点介绍了已获批准的镁基材料设备清单。此外,还讨论了当前面临的挑战和未来研究的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Magnesium based implants: Alloying and coating strategies for improvement in its biomechanical and biocorrosion properties
Magnesium (Mg) based materials show great promise as temporary implant applications owing to their biocompatibility and biodegradability. These characteristics remove the risk of subsequent surgery to extract the implant once the process of bone tissue healing is finished. Additionally, its density and elastic modulus are near to those of natural bone, thereby reducing the stress-shielding effect. Mg is mostly recognized for its osteoconductive abilities, which implies that it encourages the generation of fresh bone tissue. It also has antimicrobial properties, which lower the possibility of infections leading to implant failure. Moreover, the rapid bio-corrosion of pure Mg in the presence of physiological fluids is a serious concern. The implant's mechanical integrity deteriorates as a result of this corrosion before the surrounding tissue has completely recovered. To address these issues, this review focused on approaches, including alloying, the creation of composites, and surface coating, which can increase their biomechanical and bio-corrosion properties. In vitro analysis of biomechanical and bio-corrosion characteristics of newly manufactured Mg-based implant material is presented in this article. In addition to this application, a list of approved devices made from Mg-based material is highlighted. Furthermore, the present challenges and prospects for future research are also discussed.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
4.70
自引率
8.30%
发文量
166
审稿时长
3 months
期刊介绍: The Journal of Materials: Design and Applications covers the usage and design of materials for application in an engineering context. The materials covered include metals, ceramics, and composites, as well as engineering polymers. "The Journal of Materials Design and Applications is dedicated to publishing papers of the highest quality, in a timely fashion, covering a variety of important areas in materials technology. The Journal''s publishers have a wealth of publishing expertise and ensure that authors are given exemplary service. Every attention is given to publishing the papers as quickly as possible. The Journal has an excellent international reputation, with a corresponding international Editorial Board from a large number of different materials areas and disciplines advising the Editor." Professor Bill Banks - University of Strathclyde, UK This journal is a member of the Committee on Publication Ethics (COPE).
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信