将离散 SIS 模型的全球动态分析应用于每日报告的案例

IF 3.1 3区 数学 Q1 MATHEMATICS
Jiaojiao Wang, Qianqian Zhang, Sanyi Tang
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引用次数: 0

摘要

COVID-19 等新发传染病会爆发不同规模的疫情。对于大规模疫情,通常采用连续模型进行预测,而对于较小规模的疫情,则首选离散模型。我们提出了一个离散的易感-感染-易感模型,该模型整合了寄生虫与宿主之间的相互作用以及饱和恢复机制,并对该模型进行了深入的理论和数值探索。从理论上讲,包含非线性恢复的模型表现出复杂的行为,包括向后分叉和双重均衡的共存。研究还获得了保证无病平衡的全局渐进稳定性的充分条件。考虑到饱和恢复给理论分析带来的挑战,我们接着考虑了线性恢复的情况。对线性恢复模型的分岔分析表明,在地方病平衡点存在多种分岔,如跨临界分岔、翻转分岔和 Neimark-Sacker 分岔。数值模拟显示了复杂的动态行为,包括后向和折叠分岔、周期窗口、周期加倍级联和多稳定性。此外,所提出的模型可用于拟合各地区每日报告的 COVID-19 病例,不仅揭示了离散模型在拟合、评估和预测小规模流行病方面的显著优势,而且在评估防控策略的有效性方面也发挥了重要作用。此外,对关键参数进行的敏感性分析强调了这些参数对疫情爆发最初几个月的有效繁殖数量的重要影响,从而提倡更好地分配医疗资源和实施社会隔离措施以遏制疾病传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Global dynamic analyzes of the discrete SIS models with application to daily reported cases

Global dynamic analyzes of the discrete SIS models with application to daily reported cases

Emerging infectious diseases, such as COVID-19, manifest in outbreaks of varying magnitudes. For large-scale epidemics, continuous models are often employed for forecasting, while discrete models are preferred for smaller outbreaks. We propose a discrete susceptible-infected-susceptible model that integrates interaction between parasitism and hosts, as well as saturation recovery mechanisms, and undertake a thorough theoretical and numerical exploration of this model. Theoretically, the model incorporating nonlinear recovery demonstrates complex behavior, including backward bifurcations and the coexistence of dual equilibria. And the sufficient conditions that guarantee the global asymptotic stability of a disease-free equilibrium have been obtained. Considering the challenges posed by saturation recovery in theoretical analysis, we then consider the case of linear recovery. Bifurcation analysis for of the linear recovery model displays a variety of bifurcations at the endemic equilibrium, such as transcritical, flip, and Neimark–Sacker bifurcations. Numerical simulations reveal complex dynamic behavior, including backward and fold bifurcations, periodic windows, period-doubling cascades, and multistability. Moreover, the proposed model could be used to fit the daily COVID-19 reported cases for various regions, not only revealing the significant advantages of discrete models in fitting, evaluating, and predicting small-scale epidemics, but also playing an important role in evaluating the effectiveness of prevention and control strategies. Furthermore, sensitivity analyses for the key parameters underscore their significant impact on the effective reproduction number during the initial months of an outbreak, advocating for better medical resource allocation and the enforcement of social distancing measures to curb disease transmission.

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来源期刊
Advances in Difference Equations
Advances in Difference Equations MATHEMATICS, APPLIED-MATHEMATICS
CiteScore
8.60
自引率
0.00%
发文量
0
审稿时长
4-8 weeks
期刊介绍: The theory of difference equations, the methods used, and their wide applications have advanced beyond their adolescent stage to occupy a central position in applicable analysis. In fact, in the last 15 years, the proliferation of the subject has been witnessed by hundreds of research articles, several monographs, many international conferences, and numerous special sessions. The theory of differential and difference equations forms two extreme representations of real world problems. For example, a simple population model when represented as a differential equation shows the good behavior of solutions whereas the corresponding discrete analogue shows the chaotic behavior. The actual behavior of the population is somewhere in between. The aim of Advances in Difference Equations is to report mainly the new developments in the field of difference equations, and their applications in all fields. We will also consider research articles emphasizing the qualitative behavior of solutions of ordinary, partial, delay, fractional, abstract, stochastic, fuzzy, and set-valued differential equations. Advances in Difference Equations will accept high-quality articles containing original research results and survey articles of exceptional merit.
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