小鼠视觉皮层中颜色对立反应类型的非对称分布支持天空中的卓越色觉

IF 6.4 1区 生物学 Q1 BIOLOGY
Katrin Franke, Chenchen Cai, Kayla Ponder, Jiakun Fu, Sacha Sokoloski, Philipp Berens, Andreas Savas Tolias
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引用次数: 0

摘要

颜色是影响行为的重要视觉特征,人们已经对各种脊椎动物的色觉视网膜基础进行了研究。虽然许多研究都探讨了灵长类动物的视觉脑区是如何处理颜色信息的,但我们对其他物种(包括大多数二色性哺乳动物)视网膜以外的颜色信息组织方式的了解还很有限。在这项研究中,我们系统地描述了颜色是如何在小鼠的初级视觉皮层(V1)中表现出来的。通过大规模神经元记录以及亮度和颜色噪声刺激,我们发现小鼠 V1 中超过三分之一的神经元在其感受野中心是颜色反比的,而感受野周围则主要捕捉亮度对比。此外,我们还发现,在编码天空的后部 V1 中,颜色偏好尤其明显,这与小鼠经历的自然场景的统计数据相吻合。通过无监督聚类,我们证明了皮层中颜色表征的不对称性可以用上部视野中绿色-开/紫外-关颜色反应类型的不均匀分布来解释。最后,一个受自然场景参数刺激启发的简单模型显示,在嘈杂的日光场景中,开绿/关紫外光的颜色反应类型可能会增强对 "掠夺性 "类似暗紫外光物体的检测。这项研究的结果突显了小鼠视觉系统中颜色处理的相关性,有助于我们理解不同物种的视觉层次中如何组织颜色信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Asymmetric distribution of color-opponent response types across mouse visual cortex supports superior color vision in the sky
Color is an important visual feature that informs behavior, and the retinal basis for color vision has been studied across various vertebrate species. While many studies have investigated how color information is processed in visual brain areas of primate species, we have limited understanding of how it is organized beyond the retina in other species, including most dichromatic mammals. In this study, we systematically characterized how color is represented in the primary visual cortex (V1) of mice. Using large-scale neuronal recordings and a luminance and color noise stimulus, we found that more than a third of neurons in mouse V1 are color-opponent in their receptive field center, while the receptive field surround predominantly captures luminance contrast. Furthermore, we found that color-opponency is especially pronounced in posterior V1 that encodes the sky, matching the statistics of natural scenes experienced by mice. Using unsupervised clustering, we demonstrate that the asymmetry in color representations across cortex can be explained by an uneven distribution of green-On/UV-Off color-opponent response types that are represented in the upper visual field. Finally, a simple model with natural scene-inspired parametric stimuli shows that green-On/UV-Off color-opponent response types may enhance the detection of ‘predatory’-like dark UV-objects in noisy daylight scenes. The results from this study highlight the relevance of color processing in the mouse visual system and contribute to our understanding of how color information is organized in the visual hierarchy across species.
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来源期刊
eLife
eLife BIOLOGY-
CiteScore
12.90
自引率
3.90%
发文量
3122
审稿时长
17 weeks
期刊介绍: eLife is a distinguished, not-for-profit, peer-reviewed open access scientific journal that specializes in the fields of biomedical and life sciences. eLife is known for its selective publication process, which includes a variety of article types such as: Research Articles: Detailed reports of original research findings. Short Reports: Concise presentations of significant findings that do not warrant a full-length research article. Tools and Resources: Descriptions of new tools, technologies, or resources that facilitate scientific research. Research Advances: Brief reports on significant scientific advancements that have immediate implications for the field. Scientific Correspondence: Short communications that comment on or provide additional information related to published articles. Review Articles: Comprehensive overviews of a specific topic or field within the life sciences.
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