DuDoCROP: Dual-Domain CLIP-Assisted Residual Optimization Perception Model for CT Metal Artifact Reduction

Metal artifacts in computed tomography (CT) imaging pose significant challenges to accurate clinical diagnosis. The presence of high-density metallic implants results in artifacts that deteriorate image quality, manifesting in the forms of streaking, blurring, or beam hardening effects, etc. Nowadays, various deep learning-based approaches, particularly generative models, have been proposed for metal artifact reduction (MAR). However, these methods have limited perception ability in the diverse morphologies of different metal implants with artifacts, which may generate spurious anatomical structures and exhibit inferior generalization capability. To address the issues, we leverage visual-language model (VLM) to identify these morphological features and introduce them into a dual-domain CLIP-assisted residual optimization perception model (DuDoCROP) for MAR. Specifically, a dual-domain CLIP (DuDoCLIP) is fine-tuned on the image domain and sinogram domain using contrastive learning to extract semantic descriptions from anatomical structures and metal artifacts. Subsequently, a diffusion model is guided by the embeddings of DuDoCLIP, thereby enabling the dual-domain prior generation. Additionally, we design prompt engineering for more precise image-text descriptions that can enhance the model's perception capability. Then, a downstream task is devised for the one-step residual optimization and integration of dual-domain priors, while incorporating raw data fidelity. Ultimately, a new perceptual indicator is proposed to validate the model's perception and generation performance. With the assistance of DuDoCLIP, our DuDoCROP exhibits at least 63.7% higher generalization capability compared to the baseline model. Numerical experiments demonstrate that the proposed method can generate more realistic image structures and outperform other SOTA approaches both qualitatively and quantitatively.