腰椎间盘突出症采用椎体后凸治疗与手术治疗以及治疗后运动改善情况的比较

IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY
Kazuhiro Fujimoto , Hidenori Suzuki , Norihiro Nishida , Masahiro Funaba , Yusuke Ichihara , Hiroaki Ikeda , Yasuaki Imajo , Manabu Yamamoto , Takashi Sakai
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引用次数: 0

摘要

研究设计双中心回顾性研究。目的尚未对腰椎间盘突出症(LDH)介入治疗的使用趋势进行研究。此外,目前关于椎间盘突出症治疗后运动功能恢复的信息也很有限。因此,本研究调查了LDH治疗的使用趋势以及condoliase疗法对肌无力的影响。方法这项回顾性双中心研究涉及2017年9月至2022年8月期间接受介入治疗的LDH所致腿痛患者。LDH患者分为两组:手术治疗组和冷凝酶治疗组。2017年9月至2022年8月期间分为5等份,对干预治疗比例的变化进行了研究。此外,还对两组患者的运动恢复情况进行了评估。接受冷凝酶疗法的患者分为两组:有效组和无效组。对两组患者的性别、年龄、体重指数、症状持续时间、疝气程度、神经学和放射学检查结果、腿部疼痛视觉模拟量表和 Oswestry 残疾指数进行了检查。 结果受试者包括 226 名男性和 115 名女性,平均年龄为 49.2 岁,平均体重指数为 22.8,平均症状持续时间为 5.0 个月。冷凝酶治疗 LDH 的使用率在推出后的第三年超过了手术治疗。第四年,脊柱侧弯酶疗法成为治疗 LDH 的主要方法。结论在我们的医疗机构中,脊柱侧弯酶疗法已成为手术前的中间治疗方法。接受脊柱侧弯酶疗法的患者的运动恢复情况并不比手术后差;但是,在重症肌无力且人工肌力测试≤3的病例中,改善率约为60%。这些结果将有助于临床医生在提供知情同意和选择脊柱侧弯酶疗法时使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Utilization of condoliase therapy versus surgery for lumbar disc herniation and comparison of post-treatment motor improvement

Study Design

Double-center retrospective study.

Purpose

Utilization trends in interventional treatment for lumbar disc herniation (LDH) have not yet been examined. Furthermore, limited information is currently available on motor recovery with condoliase therapy. Therefore, the present study investigated utilization trends in treatment for LDH and the effects of condoliase therapy on muscle weakness.

Methods

This retrospective, double-center study involved patients with leg pain caused by LDH who received interventional treatment between September 2017 and August 2022. LDH patients were divided into two groups: an operative treatment group and condoliase therapy group. The period between September 2017 and August 2022 was divided into 5 equal parts and changes in the percentage of intervention treatment were examined. Motor recovery was also assessed in the two groups. Patients receiving condoliase therapy were divided into two groups: an effective group and non-effective group. Sex, age, the body mass index, duration of symptoms, herniation level, neurological and radiographic findings, a visual analog scale for leg pain, and the Oswestry disability index were examined in the two groups.

Results

Subjects included 226 males and 115 females with a mean age of 49.2 years, mean BMI of 22.8, and mean duration of symptoms of 5.0 months. The utilization of condoliase therapy for LDH surpassed surgery in the third year after its introduction. In the fourth year, condoliase therapy became the main treatment for LDH. Lower limb muscle strength improved in 76 % of cases receiving condoliase therapy.

Conclusions

Condoliase therapy has become an intermediate treatment before surgery in our institutions. Motor recovery in patients receiving condoliase therapy was not inferior to that after surgery; however, in cases with severe muscle weakness with manual muscle test ≤3, the improvement rate was approximately 60 %. These results will be useful for clinicians when providing informed consent and selecting condoliase therapy.

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来源期刊
Clinical Neurology and Neurosurgery
Clinical Neurology and Neurosurgery 医学-临床神经学
CiteScore
3.70
自引率
5.30%
发文量
358
审稿时长
46 days
期刊介绍: Clinical Neurology and Neurosurgery is devoted to publishing papers and reports on the clinical aspects of neurology and neurosurgery. It is an international forum for papers of high scientific standard that are of interest to Neurologists and Neurosurgeons world-wide.
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