急性炎症前后痛觉屈曲反射变化的非线性分析

IF 5.6 4区 医学 Q1 ENGINEERING, BIOMEDICAL
Irbm Pub Date : 2024-09-02 DOI:10.1016/j.irbm.2024.100858
Grant A. Chesbro , Jessica A. Peterson , Rebecca D. Larson , Christopher D. Black
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引用次数: 0

摘要

目的:痛觉屈曲反射(NFR)是利用肌电图(EMG)测量疼痛的一种伪客观测量方法。肌电图信号可通过非线性方法进行分析,以确定生理系统的复杂变化。生理复杂性已被证明允许系统有更广泛的适应状态来应对压力。本研究的目的是研究股二头肌在急性炎症前后受到非毒性刺激和毒性刺激时,诱发 NFR 的 EMG 信号的复杂性和熵的变化。方法和材料:12 名健康参与者(25.17 岁 ± 3.43)接受了 NFR 方案。使用赫斯特指数(H)、确定性(DET)、复发率(RR)和样本熵(SampEn)计算肌电信号复杂性。结果如下与非毒性刺激相比,在诱发 NFR 的毒性刺激中,RR(∼200%)、DET(∼70%)和 H(∼35%)更高,SampEn 降低(∼50%)。在运动诱发炎症前后,复杂性和熵的测量结果均无明显差异(p<0.05)。复杂性降低(H、DET 和 RR 增加)和规则性增加(SampEn)反映了对压力的适应性降低。结论复杂性和熵测量等非线性方法有助于了解健康的神经肌肉系统如何应对干扰。神经肌肉系统在受到有害刺激后复杂性降低,这可能反映出神经肌肉系统正在适应环境条件,以防止身体受损或受伤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Nonlinear Analysis of Nociceptive Flexion Reflex Changes Before and After Acute Inflammation

A Nonlinear Analysis of Nociceptive Flexion Reflex Changes Before and After Acute Inflammation

Objectives: The nociceptive flexion reflex (NFR) is used as a pseudo-objective measure of pain that is measured using electromyography (EMG). EMG signals can be analyzed using nonlinear methods to identify complex changes in physiological systems. Physiological complexity has been shown to allow a wider range of adaptable states for the system to deal with stressors. The purpose of this study was to examine changes in complexity and entropy of EMG signals from the biceps femoris during non-noxious stimuli and noxious stimuli that evoked the NFR before and after acute inflammation. Methods and Materials: Twelve healthy participants (25.17y ± 3.43) underwent the NFR protocol. EMG signal complexity was calculated using Hurst Exponent (H), determinism (DET), and recurrence rate (RR), and Sample Entropy (SampEn). Results: RR (∼200%), DET (∼70%), and H (∼35%) were higher and SampEn was reduced (∼50%) during the noxious stimulus that evoked the NFR compared to non-noxious stimuli. No significant differences were found for any of the complexity and entropy measures before and after exercise-induced inflammation (p<0.05). Reduced complexity (increased H, DET, and RR) and increased regularity (SampEn) reflect reduced adaptability to stressors. Conclusions: Nonlinear methods such as complexity and entropy measures could be useful in understanding how a healthy neuromuscular system responds to disturbances. The reductions in complexity following a noxious stimulus could reflect the neuromuscular system adapting to environmental conditions to prevent damage or injury to the body.

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来源期刊
Irbm
Irbm ENGINEERING, BIOMEDICAL-
CiteScore
10.30
自引率
4.20%
发文量
81
审稿时长
57 days
期刊介绍: IRBM is the journal of the AGBM (Alliance for engineering in Biology an Medicine / Alliance pour le génie biologique et médical) and the SFGBM (BioMedical Engineering French Society / Société française de génie biologique médical) and the AFIB (French Association of Biomedical Engineers / Association française des ingénieurs biomédicaux). As a vehicle of information and knowledge in the field of biomedical technologies, IRBM is devoted to fundamental as well as clinical research. Biomedical engineering and use of new technologies are the cornerstones of IRBM, providing authors and users with the latest information. Its six issues per year propose reviews (state-of-the-art and current knowledge), original articles directed at fundamental research and articles focusing on biomedical engineering. All articles are submitted to peer reviewers acting as guarantors for IRBM''s scientific and medical content. The field covered by IRBM includes all the discipline of Biomedical engineering. Thereby, the type of papers published include those that cover the technological and methodological development in: -Physiological and Biological Signal processing (EEG, MEG, ECG…)- Medical Image processing- Biomechanics- Biomaterials- Medical Physics- Biophysics- Physiological and Biological Sensors- Information technologies in healthcare- Disability research- Computational physiology- …
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