Rocahepevirus ratti:一种未被充分认识的急性肝炎病因。

IF 2.5 Q2 GASTROENTEROLOGY & HEPATOLOGY
George S Gherlan
{"title":"Rocahepevirus ratti:一种未被充分认识的急性肝炎病因。","authors":"George S Gherlan","doi":"10.4254/wjh.v16.i8.1084","DOIUrl":null,"url":null,"abstract":"<p><p>Zoonoses are responsible for many of all emerging infectious diseases as well as for those already established. <i>Rocahepevirus ratti</i> is a rat-originated virus related to the hepatitis E virus <i>(Paslahepevirus balayani)</i> but highly divergent genetically from this, with a high cross-species infection potential and zoonotic transmission. It can infect humans, leading to acute hepatitis, and is primarily transmitted through the consumption of contaminated water. <i>Rocahepevirus ratti</i> was first discovered in Germany in 2010. The first human case was described in 2017 in Hong Kong in an immune-compromised patient. The first case of chronic infection with <i>Rocahepevirus ratti</i> was described in 2023. A meta-analysis based on 38 studies published between 2000 and 2023 identified 21 cases in humans described up to this date and 489 infections in different animals. Raising awareness regarding this virus is essential, as there are probably many cases that remain undiagnosed, and the virus even has the ability to produce chronic infections in selected patients.</p>","PeriodicalId":23687,"journal":{"name":"World Journal of Hepatology","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11362906/pdf/","citationCount":"0","resultStr":"{\"title\":\"<i>Rocahepevirus ratti</i>: An underrecognised cause of acute hepatitis.\",\"authors\":\"George S Gherlan\",\"doi\":\"10.4254/wjh.v16.i8.1084\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Zoonoses are responsible for many of all emerging infectious diseases as well as for those already established. <i>Rocahepevirus ratti</i> is a rat-originated virus related to the hepatitis E virus <i>(Paslahepevirus balayani)</i> but highly divergent genetically from this, with a high cross-species infection potential and zoonotic transmission. It can infect humans, leading to acute hepatitis, and is primarily transmitted through the consumption of contaminated water. <i>Rocahepevirus ratti</i> was first discovered in Germany in 2010. The first human case was described in 2017 in Hong Kong in an immune-compromised patient. The first case of chronic infection with <i>Rocahepevirus ratti</i> was described in 2023. A meta-analysis based on 38 studies published between 2000 and 2023 identified 21 cases in humans described up to this date and 489 infections in different animals. Raising awareness regarding this virus is essential, as there are probably many cases that remain undiagnosed, and the virus even has the ability to produce chronic infections in selected patients.</p>\",\"PeriodicalId\":23687,\"journal\":{\"name\":\"World Journal of Hepatology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2024-08-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11362906/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World Journal of Hepatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4254/wjh.v16.i8.1084\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World Journal of Hepatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4254/wjh.v16.i8.1084","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

人畜共患病是许多新发传染病和已有传染病的罪魁祸首。Rocahepevirus ratti 是一种起源于老鼠的病毒,与戊型肝炎病毒(Paslahepevirus balayani)有关,但在基因上有很大差异,具有很高的跨物种感染和人畜共患传播潜力。它可感染人类,导致急性肝炎,主要通过饮用受污染的水传播。Rocahepevirus ratti 于 2010 年首次在德国被发现。2017 年,香港描述了首例人类病例,患者为一名免疫力低下的病人。2023 年描述了首例 Rocahepevirus ratti 慢性感染病例。一项基于 2000 年至 2023 年间发表的 38 项研究的荟萃分析发现,截至目前已描述了 21 例人类病例和 489 例不同动物感染病例。提高对这种病毒的认识至关重要,因为可能有许多病例仍未确诊,这种病毒甚至能够在特定患者中产生慢性感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rocahepevirus ratti: An underrecognised cause of acute hepatitis.

Zoonoses are responsible for many of all emerging infectious diseases as well as for those already established. Rocahepevirus ratti is a rat-originated virus related to the hepatitis E virus (Paslahepevirus balayani) but highly divergent genetically from this, with a high cross-species infection potential and zoonotic transmission. It can infect humans, leading to acute hepatitis, and is primarily transmitted through the consumption of contaminated water. Rocahepevirus ratti was first discovered in Germany in 2010. The first human case was described in 2017 in Hong Kong in an immune-compromised patient. The first case of chronic infection with Rocahepevirus ratti was described in 2023. A meta-analysis based on 38 studies published between 2000 and 2023 identified 21 cases in humans described up to this date and 489 infections in different animals. Raising awareness regarding this virus is essential, as there are probably many cases that remain undiagnosed, and the virus even has the ability to produce chronic infections in selected patients.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
World Journal of Hepatology
World Journal of Hepatology GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.10
自引率
4.20%
发文量
172
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信