[中药通过调节铁凋亡通路干预生精上皮损伤:研究进展]。

Q4 Medicine
中华男科学杂志 Pub Date : 2024-05-01
Jin-Tao Wei, Zi-Yang Ma, Jun Cao, Pei-Hai Zhang
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引用次数: 0

摘要

男性不育症的发病率逐年上升,其中一个主要原因是睾丸生精上皮损伤,它影响了睾丸的生精功能。铁凋亡是一种新的细胞死亡模式,在睾丸细胞损伤中发挥着重要作用。一些中药可通过调节睾丸生精上皮的铁凋亡途径,干预睾丸损伤的进展。本文重点探讨了中药在调节睾丸细胞生铁通路方面的作用,并总结了中药治疗睾丸生精上皮损伤的研究进展,旨在为相关药物的选择和临床应用提供理论依据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Intervention of traditional Chinese medicine in spermatogenic epithelium injury by regulating the ferroptosis pathway: Advances in studies].

The incidence of male infertility has been increasing year by year, and one of the major causes is testicular spermatogenic epithelial injury, which affects the spermatogenic function of the testis. Ferroptosis is a novel mode of cell death and plays an important role in testicular cell injury. Some traditional Chinese medicines can intervene in the progression of testicular injury by regulating the ferroptosis pathway in testicular spermatogenic epithelia. This paper focuses on the effect of traditional Chinese drugs in regulating the ferroptosis pathway in testicular cells, and summarizes the advances in the studies of traditional Chinese medicines in the treatment of testicular spermatogenic epithelial injury, aiming to provide a theoretical basis for the selection of relevant medicines and their clinical application.

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来源期刊
中华男科学杂志
中华男科学杂志 Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
5367
期刊介绍: National journal of andrology was founded in June 1995. It is a core journal of andrology and reproductive medicine, published monthly, and is publicly distributed at home and abroad. The main columns include expert talks, monographs (basic research, clinical research, evidence-based medicine, traditional Chinese medicine), reviews, clinical experience exchanges, case reports, etc. Priority is given to various fund-funded projects, especially the 12th Five-Year National Support Plan and the National Natural Science Foundation funded projects. This journal is included in about 20 domestic databases, including the National Science and Technology Paper Statistical Source Journal (China Science and Technology Core Journal), the Source Journal of the China Science Citation Database, the Statistical Source Journal of the China Academic Journal Comprehensive Evaluation Database (CAJCED), the Full-text Collection Journal of the China Journal Full-text Database (CJFD), the Overview of the Chinese Core Journals (2017 Edition), and the Source Journal of the Top Academic Papers of China's Fine Science and Technology Journals (F5000). It has been included in the full text of the American Chemical Abstracts, the American MEDLINE, the American EBSCO, and the database.
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