[靶向活检漏诊有临床意义的前列腺癌的原因]。

Q4 Medicine

中华男科学杂志 Pub Date : 2024-04-01

He-Song Jiang, Shan Zhou, Xiao-Bing Niu, Lu Ji

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引用次数: 0

摘要

目的回顾性分析靶向活检（TB）漏诊有临床意义的 PCa（csPCa）的原因：本回顾性研究纳入了 2018 年 6 月至 2020 年 12 月在我院发现的 PSA 升高且 MRI 信号异常的 652 名男性，年龄（71.32±16.53）岁。我们通过经会阴前列腺TB和系统活检（SB）对患者进行了进一步检查，分析了TB和SB对PCa和csPCa的检出率，并利用鱼骨图研究了TB漏诊csPCa的原因：TB联合SB对PCa和csPCa的总检出率为45.7%（298/652），csPCa的总检出率为37.4%（244/652），TB漏诊38例csPCa，其中23例为阴性TB，15例为低ISUP分级。TB漏诊 csPCa 的原因包括 MRI 图像质量低、PSA 密度≤0.15 ng/ml/cm3、靶区结论：与单独使用两种方法相比，TB 联合 SB 能产生更高的 csPCa 检出率。TB 对 csPCa 的漏诊与肿瘤特征和靶区的 MR 图像密切相关。

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本刊更多论文

[Causes of missed diagnosis of clinically significant prostate cancer by targeted biopsy].

Objective: To retrospectively analyze the causes of missed diagnosis of clinically significant PCa (csPCa) by targeted biopsy (TB).

Methods: This retrospective study included 652 males aged (71.32 ± 16.53) years with elevated PSA and abnormal MRI signals detected in our hospital from June 2018 to December 2020. We further examined the patients by transperineal prostatic TB and systematic biopsy (SB), analyzed the detection rates of PCa and csPCa by TB and SB, and investigated the causes of missed diagnosis of csPCa in TB using the fishbone diagram.

Results: The total detection rate of PCa and csPCa by TB combined with SB was 45.7% (298/652), and that of csPCa was 37.4% (244/652), with 38 cases of csPCa missed in TB, including 23 cases of negative TB and 15 cases of low ISUP grade. The causes of missed diagnosis of csPCa by TB included low MRI image quality, PSA density ≤0.15 ng/ml/cm3, target area <10 mm, and PI-RADS 2 score ≤3. The detection rate of csPCa by TB alone was 31.6%, which was increased by 5.8% (P = 0.027) when TB combined with SB.

Conclusion: TB combined with SB yields a higher detection rate of csPCa than either used alone. Missed diagnosis of csPCa by TB is closely related to the characteristics of tumor and MR image of the target area.

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来源期刊

中华男科学杂志 Medicine-Medicine (all)

CiteScore

0.40

自引率

0.00%

发文量

5367

期刊介绍： National journal of andrology was founded in June 1995. It is a core journal of andrology and reproductive medicine, published monthly, and is publicly distributed at home and abroad. The main columns include expert talks, monographs (basic research, clinical research, evidence-based medicine, traditional Chinese medicine), reviews, clinical experience exchanges, case reports, etc. Priority is given to various fund-funded projects, especially the 12th Five-Year National Support Plan and the National Natural Science Foundation funded projects. This journal is included in about 20 domestic databases, including the National Science and Technology Paper Statistical Source Journal (China Science and Technology Core Journal), the Source Journal of the China Science Citation Database, the Statistical Source Journal of the China Academic Journal Comprehensive Evaluation Database (CAJCED), the Full-text Collection Journal of the China Journal Full-text Database (CJFD), the Overview of the Chinese Core Journals (2017 Edition), and the Source Journal of the Top Academic Papers of China's Fine Science and Technology Journals (F5000). It has been included in the full text of the American Chemical Abstracts, the American MEDLINE, the American EBSCO, and the database.