COVID-19 大流行期间髋部骨折患者的 90 天发病率和死亡率增加。

IF 1.1 4区 医学 Q3 ORTHOPEDICS
Orthopedics Pub Date : 2024-11-01 Epub Date: 2024-09-04 DOI:10.3928/01477447-20240826-03
Megan M Mizera, Danielle Putur, Anna Tarasova, Edina Gjonbalaj, Zeynep Seref-Ferlengez, Andrea M Muñoz, Noel O Akioyamen, Mani Kahn
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引用次数: 0

摘要

背景:当冠状病毒病 2019(COVID-19)首次传播到美国时,我们的医疗机构正处于疫情中心。尽管对 COVID-19 的长期影响了解有限,但我们仍严格按照指南对老年髋部骨折进行了手术固定。本研究对这些患者在疫情爆发期间的治疗效果与疫情爆发前的治疗效果进行了比较:我们对本地区大流行高峰期(2019 年 12 月至 2020 年 6 月)的髋部骨折患者进行了回顾性队列研究。将接受手术固定治疗的患者(2020 年队列)的结果与历史对照组(2019 年队列)的结果进行了比较。主要结果是 90 天死亡率,次要结果包括肺炎、血栓栓塞事件、急诊就诊、再入院和心脏事件:2020年队列(64人)和2019年队列(78人)的基线特征相似。与大流行前队列相比,2020年队列患肺炎的风险高出4.27倍(95% CI,1.30-13.98),但在90天并发症方面没有其他差异。2020 年队列中的 COVID-19 患者患肺炎的风险是流行前队列的 5.09 倍(95% CI,1.35-19.20),术后死亡率是流行前队列的 5.38 倍(95% CI,1.13-25.64)。由于所有患者都接受了肝素抗凝治疗,因此2020年队列和2019年队列之间的血栓栓塞风险没有增加,即使是COVID-19病例也是如此:我们的研究表明,在美国COVID-19大流行的高峰期,髋部骨折手术仍然是安全的,预计COVID-19会增加髋部骨折患者的肺炎和死亡风险。[骨科。202x;4x(x):xx-xx]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Increased 90-Day Morbidity and Mortality Among Patients With Hip Fracture During the COVID-19 Pandemic.

Background: When coronavirus disease 2019 (COVID-19) first spread to the United States, our institution was at the outbreak's epicenter. Despite limited understanding of COVID-19's long-term effects, we continued performing surgical fixation of geriatric hip fractures under strict guidelines. This study examined the outcomes of these patients during the pandemic compared with those of patients treated pre-pandemic.

Materials and methods: We conducted a retrospective cohort study of patients with hip fractures between December 2019 and June 2020, the peak of the pandemic in our region. Outcomes of patients treated with surgical fixation (2020 cohort) were compared with those of a historical control group (2019 cohort). The primary outcome was 90-day mortality, with secondary outcomes including pneumonia, thromboembolic events, emergency department visits, readmission, and cardiac events.

Results: The 2020 cohort (n=64) and 2019 cohort (n=78) had similar baseline characteristics. The 2020 cohort had a 4.27 times higher risk (95% CI, 1.30-13.98) of developing pneumonia compared with the pre-pandemic cohort but had no other differences in 90-day complications. Patients with COVID-19 in the 2020 cohort had a 5.09 times higher risk (95% CI, 1.35-19.20) of developing pneumonia and a 5.38 times higher risk (95% CI, 1.13-25.64) of postoperative mortality. There was no increased risk for thromboembolism between the 2020 and 2019 cohorts, even among COVID-19 cases, as all patients received anticoagulation with heparin.

Conclusion: Our study demonstrates that hip fracture surgery remained safe during the peak of the US COVID-19 pandemic, with an expected increase in pneumonia and mortality risk for patients with hip fracture with COVID-19. [Orthopedics. 2024;47(6):359-364.].

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来源期刊
Orthopedics
Orthopedics 医学-整形外科
CiteScore
2.20
自引率
0.00%
发文量
160
审稿时长
3 months
期刊介绍: For over 40 years, Orthopedics, a bimonthly peer-reviewed journal, has been the preferred choice of orthopedic surgeons for clinically relevant information on all aspects of adult and pediatric orthopedic surgery and treatment. Edited by Robert D''Ambrosia, MD, Chairman of the Department of Orthopedics at the University of Colorado, Denver, and former President of the American Academy of Orthopaedic Surgeons, as well as an Editorial Board of over 100 international orthopedists, Orthopedics is the source to turn to for guidance in your practice. The journal offers access to current articles, as well as several years of archived content. Highlights also include Blue Ribbon articles published full text in print and online, as well as Tips & Techniques posted with every issue.
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