β-磷酸三钙、Plasmogel 和富血小板血浆的组合可改善并发症下第三磨牙手术后的长期骨组织修复:非随机对照试验。

IF 0.9 Q3 DENTISTRY, ORAL SURGERY & MEDICINE
Contemporary Clinical Dentistry Pub Date : 2024-04-01 Epub Date: 2024-07-10 DOI:10.4103/ccd.ccd_544_23
Madina Amanzholovna Mugalbayeva, Ulmeken Rakhimovna Mirzakulova, Gulbaran Baigazinovna Zaitenova, Zharkinbek Shertajuly Uglanov
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引用次数: 0

摘要

背景:手术拔除下第三磨牙会导致一系列并发症,而骨修复通常需要大量时间。本研究旨在通过 X 射线研究β-磷酸三钙(β-TCP)、血浆凝胶和富血小板血浆的组合对术后骨组织修复的影响:共有 200 名接受复杂下第三磨牙拔除术的患者被非随机分配到实验组(EXP,n = 100)或对照组(CTR,n = 100)。在 EXP 组患者中,牙槽窝由 β-TCP、血浆凝胶和富血小板血浆组合填充。CTR 组患者的牙槽窝未进行处理。术后 3、6 和 9 个月(T1、T2 和 T3)进行 X 光检查,根据 Misch 标度确定骨质情况。组间比较采用 Mann-Whitney U 检验:除了糖类摄入过多(CTR 组更经常摄入糖类)和性别比例差异略微显著(CTR 组女性更多)之外,两组患者的情况相当。虽然随着时间的推移,两组的骨密度都有所提高,但 EXP 组在 T1(U = 3431,P < 0.001)、T2(U = 3190,P < 0.001)和 T3(U = 3505,P < 0.001)时的骨密度恢复程度更高,这与 D2(嵴上致密的厚多孔皮质骨和底层粗小梁骨)的比例更高有关:结论:与不采取任何治疗措施相比,β-TCP、血浆凝胶和富血小板血浆联合疗法有助于下第三磨牙复杂手术切除后的骨组织恢复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Combination of Beta-tricalcium Phosphate, Plasmogel, and Platelet-rich Plasma Improves Long-term Bone Tissue Restoration after Complicated Lower Third Molar Surgery: A Nonrandomized Controlled Trial.

Background: A surgical removal of the lower third molars can lead to a number of complications, and bone restoration typically takes a large amount of time. The aim of the study was to investigate the effect of the combination of beta-tricalcium phosphate (β-TCP), plasmogel, and platelet-rich plasma on postsurgery bone tissue restoration by means of X-ray.

Subjects and methods: A total of 200 patients who underwent a complicated removal of the lower third molars were nonrandomly assigned to the experimental (EXP, n = 100) or control (CTR, n = 100) group. In the EXP group patients, sockets were filled with a combination of β-TCP, plasmogel, and platelet-rich plasma. In the CTR group, sockets were not treated. X-ray examinations were performed 3, 6, and 9 months (T1, T2, and T3) postsurgery to define bone quality on the Misch scale. The Mann-Whitney U-test was used for between-group comparison.

Results: Aside from the overconsumption of sugars (more frequently in CTR) and marginally significant sex ratio difference (more females in CTR), the groups were equivalent. Although both groups improved on bone density with time, the EXP group demonstrated greater restoration at T1 (U = 3431, P < 0.001), T2 (U = 3190, P < 0.001), and T3 (U = 3505, P < 0.001) related to a greater percentage of D2 (dense thick porous cortical bone on the ridge and a coarse underlying trabecular bone).

Conclusion: A combination of β-TCP, plasmogel, and platelet-rich plasma, compared to no treatment, facilitates bone tissue restoration after complicated surgical removal of the lower third molars.

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来源期刊
Contemporary Clinical Dentistry
Contemporary Clinical Dentistry DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
1.50
自引率
0.00%
发文量
52
审稿时长
23 weeks
期刊介绍: The journal Contemporary Clinical Dentistry (CCD) (Print ISSN: 0976-237X, E-ISSN:0976- 2361) is peer-reviewed journal published on behalf of Maharishi Markandeshwar University and issues are published quarterly in the last week of March, June, September and December. The Journal publishes Original research papers, clinical studies, case series strictly of clinical interest. Manuscripts are invited from all specialties of Dentistry i.e. Conservative dentistry and Endodontics, Dentofacial orthopedics and Orthodontics, Oral medicine and Radiology, Oral pathology, Oral surgery, Orodental diseases, Pediatric Dentistry, Periodontics, Clinical aspects of Public Health dentistry and Prosthodontics. Review articles are not accepted. Review, if published, will only be by invitation from eminent scholars and academicians of National and International repute in the field of Medical/Dental education.
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